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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/9920

Title: Intraspinal Dermoid and Epidermoid Tumors: Report of 18 Cases and Reappraisal of the Literature
Authors: van Aalst, J.
Hoekstra, F.
BEULS, Emile
Cornips, E. M. J.
Weber, J. W.
Sival, D. A.
Creytens, D. H. K. V.
Vles, J. S. H.
Issue Date: 2009
Publisher: KARGER
Citation: PEDIATRIC NEUROSURGERY, 45(4). p. 281-290
Abstract: Intraspinal dermoid and epidermoid tumors are two histopathological subtypes of cutaneous inclusion tumors of the spine. This classification is based on obsolete embryological knowledge. In fact, according to current embryology, both tumor types consist of ectodermal derivatives. Therefore, we hypothesized that dermoid and epidermoid tumors do not differ in clinical practice. To explore this hypothesis, we studied the clinical, radiological and intraoperative findings of 18 patients, and related these findings to the histopathological characteristics of the tumor. No differences were found between dermoid and epidermoid tumors regarding clinical presentation, radiological examination and outcome, while intraoperative diagnosis by the surgeon correlated with the histopathological diagnosis in only 8 of 18 cases. Therefore, the histopathological difference between intraspinal dermoid and epidermoid tumors is not important in clinical practice and should be avoided. A new nomenclature is proposed in which both tumor types are referred to as 'spinal cutaneous inclusion tumors'. Copyright (C) 2009 S. Karger AG, Basel
Notes: [van Aalst, J.; Hoekstra, F.; Beuls, E. A. M.; Cornips, E. M. J.] Univ Med Ctr Maastricht, Dept Neurosurg, Maastricht, Netherlands. [Weber, J. W.; Vles, J. S. H.] Univ Med Ctr Maastricht, Dept Child Neurol, Maastricht, Netherlands. [Creytens, D. H. K. V.] Univ Med Ctr Maastricht, Dept Pathol, Maastricht, Netherlands. [Sival, D. A.] Univ Med Ctr Groningen, Dept Child Neurol, NL-9713 AV Groningen, Netherlands. [Beuls, E. A. M.] Univ Hasselt, Dept Basic Med Sci, Diepenbeek, Belgium.
URI: http://hdl.handle.net/1942/9920
DOI: 10.1159/000235602
ISI #: 000269788000006
ISSN: 1016-2291
Category: A1
Type: Journal Contribution
Validation: ecoom, 2010
Appears in Collections: Research publications

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