Document Server@UHasselt >
Research >
Research publications >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/8094

Title: Metallothionein: a possible new marker for human dental pulp stem cells
Authors: STRUYS, Tom
Krage, Tracy
Issue Date: 2007
Publisher: Scientists for scientists
Citation: European Cells and Materials - Supplements, 14(2). p. 131-131
Abstract: Human dental pulp stem cells (HDPSC’s) is a term used for the remaining mesenchymal stem cell population in adult teeth. It has already been described that these cells exhibit odontogenic capacities when these cells are explanted into immunocompromised mice. They create a dentin-pulp like complex and in this way their use in tissue engineering and tooth regeneration seems very promising. However, there is still a lack of specific markers to identify this cell type. In this study, we investigated the immunoreactivity of HDPSC’s for metallothionein (MT), a Cystein-rich, low molecular weight protein. MT has the capacity to bind both physiological (Zn, Cu, Se,...) and xenobiotic (Cd, Hg, Ag,...) heavy metals through the thiol group of its cysteine residues. Furthermore, the immunoreactivity fot MT was tested in human pulp tissue and human bone-marrow derived mesenchymal stem cells.
Notes: Abstracts of the 9th International Conference on Tooth Morphogenesis and Differentiation
URI: http://hdl.handle.net/1942/8094
Link to publication: http://www.ecmjournal.org/journal/supplements/vol014supp02/pdf/v014supp02a131.pdf
ISSN: 1473-2262
Category: A2
Type: Journal Contribution
Appears in Collections: Research publications

Files in This Item:

Description SizeFormat
Published version33.24 kBAdobe PDF

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.