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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/7959

Title: Social contact and mixing patterns relevant to the spread of infectious diseases: a multi-country population-based survey
Authors: Mossong, J
Jit, M
HENS, Niel
Beutels, P
Auranen, K.
Mikolajczyk, R
Massari, M.
Scalia-Tomba, GP
Wallinga, J
Sadkowska-Todys, M
Rosinska, M
Edmunds, WJ
Issue Date: 2007
Abstract: Background: Mathematical modelling of infectious diseases transmitted by the respiratory or close-contact route(e.g., pandemic influenza, is increasingly being used to determine the impact of possible interventions. Although mixing patterns are known to be crucial determinants for model outcome, researchers often rely on a priori contact assumptions with little or no empirical basis. We conducted a population-based prospective survey of mixing patterns in eight European countries using a common paper-diary methodology. Methods and findings: 7290 participants recorded characteristics of 97.904 contacts with different individuals during one day, including age, sex, location, duration, frequency, and occurrence of physical contact. We found that mixing patterns and contact characteristics were remarkably similar across different European countries. Contact patterns were highly assortive with age: schoolchildren and young adults in paticular tended to mix with people of the same age. Contacts lasting at least one hour or occurring on a daily basis mostly involved physical contact, while short duration and infrequent contacts tended to be nonphysical. Contacts at home, school or leisure were more likely to be physical than contacts at the workplace or while travelling. Preliminary modelling indicates that 5- to 19-year-olds are expected to suffer the highest incidence during the initial epidemic phase of an emerging infection transmitted through social contacts measured here when the population in completed susceptible. Conclusions: To our knowledge, our study provides the first large-scale quantitative approach to contact patterns relevant for infections transmitted by the respiratory or close-contact route, and the results should lead to improved parameterisation of mathematical models used to design control strategies.
Notes: Lab Natl St Luxembourg, Luxembourg, Luxembourg. Hlth Protect Agcy, Colindale, England. Univ Hasselt, Diepenbeek, Belgium. Univ Antwerp, B-2020 Antwerp, Belgium. Natl Publ Hlth Inst, KTL, Helsinki, Finland. Univ Bielefeld, D-4800 Bielefeld, Germany. Ist Super Sanita, I-00161 Rome, Italy. Univ Roma, Rome, Italy. RIVM, Bilthoven, Netherlands. Natl Inst Hyg, PL-00791 Warsaw, Poland.
URI: http://hdl.handle.net/1942/7959
DOI: 10.1093/eurpub/ckm1004
ISI #: 000251544100146
ISSN: 1101-1262
Category: M
Type: Journal Contribution
Appears in Collections: Research publications

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