Document Server@UHasselt >
Research publications >
Please use this identifier to cite or link to this item:
|Title: ||Non-compliance, ethical imperative or mission impossible?|
|Authors: ||GOETGHEBEUR, Els|
|Issue Date: ||1996|
|Citation: ||Statistics in medicine, 15(24). p. 2813-2826|
|Abstract: ||Assuming that a drug is active and different from placebo, a patient's gain or loss is likely to depend on how much of the drug is taken and when. The present paper motivates the ethical imperative of statistical compliance analysis by considering important clinical questions, the advent of more precise compliance measuring instruments and new statistical efforts towards well understood analyses that seek to preserve scientific integrity. An extension of Efron and Feldman's approach is developed which exploits the randomization assumption in combination with structural models. It also generates more promising designs and alternative statistical approaches.|
|Type: ||Journal Contribution|
|Appears in Collections: ||Research publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.