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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/6711

Title: Racemization of aspartic acid from human dentin in the estimation of chronological age
Authors: Yekkala, R.
Meers, Carine
van Schepdael, A.
Hoogmartens, J.
Willems, G.
Issue Date: 2006
Citation: Forensic science international, 159(S1). p. S89-S94
Abstract: The estimation of chronological age in cadavers, human remains and in living human beings by various methods is discussed. These methods, which are based on the age dependent non-enzymatic changes of l-form amino acids to d-form amino acids, mainly aspartic acid, are among the most reliable and accurate methods to date. Most of these methods use gas chromatography (GC). In this review, results of aspartic acid racemization in dentin at different targets are discussed. In addition, pre-considerations and guidelines are given for the selection of dentin from teeth. A pilot project was run to evaluate the efficiency of high performance liquid chromatography (HPLC) coupled with fluorescence detection. New buffer conditions were found to obtain stable derivatives of aspartic acid enantiomers for the estimation of racemization.
URI: http://hdl.handle.net/1942/6711
DOI: 10.1016/j.forsciint.2006.02.022
ISI #: 000237598700019
ISSN: 0379-0738
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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