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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/6178

Title: Heterogeneous random-effects models for screening of prostate cancer
Authors: Brant, L.J.
Sheng, S.L.l
Morrell, C.H.
Carter, H.B.
Issue Date: 2003
Publisher: Blackwell Publishing
Citation: Journal of the Royal Statistical Society: series A: statistics in society, 166(1). p. 51-62
Abstract: Random-effects models are used to screen male participants in a long-term longitudinal study for prostate cancer. By using posterior probabilities, each male can be classified into one of four diagnostic states for prostate disease: normal, benign prostatic hyperplasia, local cancer and metastatic cancer. Repeated measurements of prostate-specific antigen, collected when there was no clinical evidence of prostate disease, are used in the classification process. An individual's screening data are considered one repeated measurement at a time as his data are collected longitudinally over time. Posterior probabilities are calculated on the basis of data from other individuals with confirmed diagnoses of each of the four diagnostic states.
URI: http://hdl.handle.net/1942/6178
DOI: 10.1111/1467-985X.00258
Category: A2
Type: Journal Contribution
Appears in Collections: Research publications

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