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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/3630

Title: POLYMORPHISM OF THE TUMOR-NECROSIS-FACTOR BETA-GENE IN MULTIPLE-SCLEROSIS AND RHEUMATOID-ARTHRITIS
Authors: VANDEVYVER, Caroline
RAUS, P
CASSIMAN, JJ
RAUS, Jef
STINISSEN, Piet
PHILIPPAERTS, Linda
Issue Date: 1994
Publisher: BLACKWELL SCIENCE LTD
Citation: EUROPEAN JOURNAL OF IMMUNOGENETICS, 21(5). p. 377-382
Abstract: We evaluated the TNF-beta gene polymorphism in two HLA-associated autoimmune diseases, multiple sclerosis (MS) and rheumatoid arthritis (RA). The TNF-beta allele and genotype frequencies were not significantly different in the patient populations, compared to controls. An increased frequency of the TNF-beta*2 allele was observed in HLA-DR2(+) vs. HLA-DR2(-) MS patients. No such association was seen in HLA-DR4(+) RA patients.
Notes: LIMBURGS UNIV CENTRUM,DIEPENBEEK,BELGIUM. GASTHUISBERG LOUVAIN,ONDERWIJS NAVORSING,CENTRUM MENSELIJKE ERFELIJKHEID,LOUVAIN,BELGIUM.VANDEVYVER, C, DR L WILLEMS INST,DEPT IMMUNOL BIOTECHNOL,UNIV CAMPUS,B-3590 DIEPENBEEK,BELGIUM.
URI: http://hdl.handle.net/1942/3630
ISI #: A1994PK35500009
ISSN: 0960-7420
Type: Journal Contribution
Appears in Collections: Research publications

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