Document Server@UHasselt >
Research publications >
Please use this identifier to cite or link to this item:
|Title: ||The structural aspects of the flabby ridge or alveolar fibrosis.|
|Authors: ||Thevissen, E|
|Issue Date: ||1997|
|Publisher: ||AMER ASSOC DENTAL RESEARCH|
|Citation: ||JOURNAL OF DENTAL RESEARCH, 76(5). p. 1125-1125|
|Abstract: ||A flabby ridge or alveolar fibrosis is a dcnture-induced change of the oral mucosa. The
flabby ridge originates when parts of the alveolar ridge becomes resorbed duc to excessive
occlusal trauma on she denture in the affected area.
In this case dlsc oral mucosa at the level of the flabby ridgc was studied using light
microscopy, electron microscopy and inununohaislochemistry. The structures were
compared with the normal oral mucosa of the maxilla.
The flabby ridge was surgically removed and the specimens were immediately fixed in
glutaraldehyde and further processed for light snicroscopy (paraffine embedding) and
electron microscopy (aralditc embedding). Monoclomial antibodies against the Nervc
Growth Factor Receptor (NGFR) anid the netirofilament proteiu (NF) were applicd to the
specimens using the APAAP inethod. Special attention has been given to the
inflammatory cells and especially to the mastocytes. The latter were stained using the
high Iron and the May Grtiiiwald Giemsa method on paraffine sections and thionist
snethlylen blue on aralditc sections. The flabby ridge prcsented a higha degree of
issflammation combined witd fibrosis of the submucosa. The isnmunoreaclivity for NGFR
and NF was decreased. The nunmber of neiec fibres in dlee connective tissue of the lamina
propioa was low in comparison with the neural distribution in the nonnal oral mucosa.|
|Notes: ||LIMBURGS UNIV CTR,DEPT MBW,DIEPENBEEK,BELGIUM. CATHOLIC UNIV,DEPT PERIOD,LOUVAIN,BELGIUM.|
|ISI #: ||A1997WW07501362|
|Type: ||Journal Contribution|
|Appears in Collections: ||Research publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.