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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/2955

Title: Radiographic imaging: the 'gold standard' for assessment of disease progression in rheumatoid arthritis
Authors: VAN DER HEIJDE, Desiree
Issue Date: 2000
Citation: RHEUMATOLOGY, 39. p. 9-16
Abstract: Rheumatoid arthritis (RA) is characterized by a chronic inflammation of the joints, which leads to the destruction of articular cartilage and bone. The degree of joint damage assessed by radiographic imaging represents a key outcome in RA. There are several methods for scoring the joint damage associated with RA. The most widely used are the Sharp and Larsen systems, as well as more recent modifications of each method. Radiographic imaging has several advantages compared with other outcome measures in RA, specifically: X-rays reflect the history of joint pathology, provide a permanent record for serial evaluation, and can be randomized and blinded for objective scoring. Several modifications of these methods have been proposed and employed in the investigation of disease progression. A review of the radiographic progression of RA is presented, as well as a simplified scoring system useful for the evaluation of joint damage in RA in a clinical setting.
Notes: Univ Hosp Maastricht, Dept Internal Med, Div Rheumatol, NL-6202 AZ Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium.van der Heijde, DMFM, Univ Hosp Maastricht, Dept Internal Med, Div Rheumatol, POB 5800, NL-6202 AZ Maastricht, Netherlands.
URI: http://hdl.handle.net/1942/2955
ISI #: 000087832200003
ISSN: 1462-0324
Category: A1
Type: Journal Contribution
Validation: ecoom, 2001
Appears in Collections: Research publications

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