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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/28819

Title: A new imaging technology to reduce the radiation dose during uterine fibroid embolization
Authors: Thomaere, Eveline
Dehairs, Michiel
Laenen, Annouschka
Mehrsima, Abdoli
Timmerman, Dirk
Cornelissen, Sandra
Op de Beeck, Katya
Bosmans, Hilde
Maleux, Geert
Issue Date: 2018
Citation: ACTA RADIOLOGICA, 59(12), p. 1446-1450
Abstract: Background: Uterine fibroid embolization (UFE) is a minimally invasive imaging-guided treatment using radiation exposure. Purpose: To compare the patients' radiation exposure during UFE before and after introduction of a new X-ray imaging platform. Material and Methods: Forty-one patients were enrolled in a prospective, comparative two-arm project before and after introduction of a new X-ray imaging platform with reduced dose settings, i.e. novel real-time image processing techniques (AlluraClarity). Demographic, pre-interventional imaging, and procedural data, including dose area product (DAP) and estimated organ dose on the ovaries and uterus, were recorded and angiographic quality of overall procedure was assessed. Results: There were no significant differences in demographic characteristics and preoperative fibroid and uterine volumes in the two groups. The new imaging platform led to a significant reduction in mean total DAP (102 vs. 438 Gy.cm(2); P < 0.001), mean fluoroscopy DAP (32 vs. 138 Gy.cm(2); P < 0.001), mean acquisition DAP (70 vs. 300 Gy.cm(2); P < 0.001), and acquisition DAP estimated organ dose in ovaries (42 vs. 118 mGy; P < 0.001) and uterus (40 vs. 118 mGy, P < 0.001), without impairment of the procedure and angiographic image quality. Conclusion: A substantial 77% reduction of DAP values and 64% and 66% reduction in organ dose on ovaries and uterus, respectively, was demonstrated with the new imaging platform, while maintaining optimal imaging quality and efficacy.
Notes: [Thomaere, Eveline; de Beeck, Katya Op] Katholieke Univ Leuven, Dept Radiol, Univ Hosp Leuven, Dept Imaging & Pathol, Leuven, Belgium. [Dehairs, Michiel; Bosmans, Hilde] Katholieke Univ Leuven, Sect Med Phys, Dept Radiol, Univ Hosp Leuven,Dept Imaging & Pathol, Leuven, Belgium. [Laenen, Annouschka] Katholieke Univ Leuven, Interuniv Ctr Biostat & Stat Bioinformat, Leuven, Belgium. [Laenen, Annouschka] Univ Hasselt, Leuven, Belgium. [Mehrsima, Abdoli] Philips Healthcare, Eindhoven, Netherlands. [Timmerman, Dirk] Univ Hosp Leuven, Dept Gynecol, Leuven, Belgium. [Cornelissen, Sandra; Maleux, Geert] Katholieke Univ Leuven, Dept Radiol, Sect Intervent Radiol, Univ Hosp Leuven,Dept Imaging & Pathol, Herestr 49, B-3000 Leuven, Belgium.
URI: http://hdl.handle.net/1942/28819
DOI: 10.1177/0284185118760064
ISI #: 000453426300012
ISSN: 0284-1851
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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