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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/287

Title: Topics in Modelling of Clustered Data
Authors: Aerts, Marc
Geys, Helena
Molenberghs, Geert
Ryan, Louise
Keywords: Clustered data
Longitudinal data
Issue Date: 2002
Publisher: Chapman and Hall
Series/Report: Chapman & Hall/CRC Monographs on Statistics & Applied Probability
Series/Report no.: 96
Abstract: Many methods for analyzing clustered data exist, all with advantages and limitations in particular applications. Compiled from the contributions of leading specialists in the field, Topics in Modelling of Clustered Data describes the tools and techniques for modelling the clustered data often encountered in medical, biological, environmental, and social science studies. It focuses on providing a comprehensive treatment of marginal, conditional, and random effects models using, among others, likelihood, pseudo-likelihood, and generalized estimating equations methods. The authors motivate and illustrate all aspects of these models in a variety of real applications. They discuss several variations and extensions, including individual-level covariates and combined continuous and discrete outcomes. Flexible modelling with fractional and local polynomials, omnibus lack-of-fit tests, robustification against misspecification, exact, and bootstrap inferential procedures all receive extensive treatment. The applications discussed center primarily, but not exclusively, on developmental toxicity, which leads naturally to discussion of other methodologies, including risk assessment and dose-response modelling. Clearly written, Topics in Modelling of Clustered Data offers a practical, easily accessible survey of important modelling issues. Overview models give structure to a multitude of approaches, figures help readers visualize model characteristics, and a generous use of examples illustrates all aspects of the modelling process.
URI: http://hdl.handle.net/1942/287
ISBN: 9781584881858
Category: B3
Type: Book
Appears in Collections: Research publications

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