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|Title: ||Acute responses of cytokines and adipokines to aerobic exercise in relapsing vs. remitting women with multiple sclerosis|
|Authors: ||Majdinasab, Nastaran|
Motl, Robert W.
Baker, Julien S.
|Issue Date: ||2018|
|Citation: ||COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE, 31, p. 295-301|
|Abstract: ||Objective: To examine the acute effect of exercise on cytokines and adipokines during relapse and the remitting phase of multiple sclerosis (MS). Methods: Thirty women with MS in the relapsing or remitting phase were matched with fifteen healthy controls. Participants performed a single-bout of aerobic exercise at 60-70% maximal heart rate. Furthermore, five women in the relapsing phase were enrolled (control relapse) and did not receive any intervention. Blood samples were taken before, immediately after, 1-h and 6-h after the exercise. Results: Levels of IL-10 and TNF-alpha in response to exercise were similar in healthy and MS remitting subjects. Compared to baseline, TNF-alpha levels in relapsing subjects were significantly decreased immediately after exercise. Immediately following exercise, leptin levels significantly decreased in relapsing subjects. Adiponectin and IL-6 showed no significant difference between groups. Conclusion: After relapse, exercise does not induce inflammatory cytokine response and temporarily improves both cytokine and adipokine balance. (C) 2018 Elsevier Ltd. All rights reserved.|
|Notes: ||Mokhtarzade, M (reprint author), Ahvaz Jundishapur Univ Med Sci, Sch Med, Musculoskeletal Rehabil Res Ctr, Ahwaz, Iran. email@example.com|
|ISI #: ||000432520800044|
|Type: ||Journal Contribution|
|Appears in Collections: ||Research publications|
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|Published version||723.45 kB||Adobe PDF|
|Peer-reviewed author version||1.61 MB||Adobe PDF|
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