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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/26419

Title: Towards a contemporary, comprehensive scoring system for determining technical outcomes of hybrid percutaneous chronic total occlusion treatment: The RECHARGE score
Authors: Maeremans, Joren
Spratt, James C.
Knaapen, Paul
Walsh, Simon
Agostoni, Pierfrancesco
Wilson, William
Avran, Alexandre
Faurie, Benjamin
Bressollette, Erwan
Kayaert, Peter
Bagnall, Alan J.
Smith, Dave
McEntegart, Margaret B.
Smith, William H. T.
Kelly, Paul
Irving, John
Smith, Elliot J.
Strange, Julian W.
Dens, Jo
Issue Date: 2018
Abstract: ObjectivesThis study sought to create a contemporary scoring tool to predict technical outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) from patients treated by hybrid operators with differing experience levels. BackgroundCurrent scoring systems need regular updating to cope with the positive evolutions regarding materials, techniques, and outcomes, while at the same time being applicable for a broad range of operators. MethodsClinical and angiographic characteristics from 880 CTO-PCIs included in the REgistry of CrossBoss and Hybrid procedures in FrAnce, the NetheRlands, BelGium and UnitEd Kingdom (RECHARGE) were analyzed by using a derivation and validation set (2:1 ratio). Variables significantly associated with technical failure in the multivariable analysis were incorporated in the score. Subsequently, the discriminatory capacity was assessed and the validation set was used to compare with the J-CTO score and PROGRESS scores. ResultsTechnical success in the derivation and validation sets was 83% and 85%, respectively. Multivariate analysis identified six parameters associated with technical failure: blunt stump (beta coefficient (b)=1.014); calcification (b=0.908); tortuosity 45 degrees (b=0.964); lesion length 20mm (b=0.556); diseased distal landing zone (b=0.794), and previous bypass graft on CTO vessel (b=0.833). Score variables remained significant after bootstrapping. The RECHARGE score showed better discriminatory capacity in both sets (area-under-the-curve (AUC)=0.783 and 0.711), compared to the J-CTO (AUC=0.676) and PROGRESS (AUC=0.608) scores. ConclusionsThe RECHARGE score is a novel, easy-to-use tool for assessing the risk for technical failure in hybrid CTO-PCI and has the potential to perform well for a broad community of operators. (c) 2017 Wiley Periodicals, Inc.
Notes: Dens, J (reprint author), Schiepse Bos 6, B-3600 Genk, Belgium. jo.dens@zol.be
URI: http://hdl.handle.net/1942/26419
DOI: 10.1002/ccd.27092
ISI #: 000424223600004
ISSN: 1522-1946
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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