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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/2628

Title: The relationship among history of falls, osteoporosis, and fractures in postmenopausal women
Authors: GEUSENS, Piet
Autier, P
Declerck, K
Issue Date: 2002
Publisher: W B SAUNDERS CO
Abstract: Objective: To study the relative contribution of osteoporosis and falls to the occurrence of symptomatic fractures in postmenopausal women. Design: Retrospective survey of current osteoporosis in relation to falls and fractures in the preceding year. Setting: Patients of general practitioners of the area around a Belgian university. Participants: A total of 2649 consecutive postmenopausal women (mean age, 61y; range, 45-91y). Interventions: Not applicable. Main Outcome Measures: Current bone density measurements (single-photon absorptiometry in the forearm) were analyzed in relation to self-reported incidence of falls and fractures in the preceding year. Results: Osteoporosis was found in 15% of the patients, 19% reported I or more falls during the preceding year, and 1.8% had a fracture during the preceding year. The age-adjusted risk for a fracture in the past 12 months for a I standard deviation decrease in bone density was 1.9 (95% confidence interval [CI], 1.4-2.5; P<.01). Adjusted risk for age, bone density, and body mass index (BMI) for a fracture in the past 12 months in patients who reported a fall was 6.0 (95% Cl, 3.1-11.5; P<.001). Compared with women without osteoporosis and without a fall, women with osteoporosis without a fall had an age- and BMI-adjusted fracture risk of 2.8 (95% CI 0.6-12.8; P<.10), and women with osteoporosis and a fali had an adjusted-fracture risk of 24.8 (95% CI, 6.9-88.6; P<.0001). Conclusions: Falls are a major contributing factor to the occurrence of symptomatic fractures in postmenopausal women, independent of and additive to the risk attributable to age and osteoporosis.
Notes: Limburgs Univ Ctr, Inst Biomed Res, B-3590 Diepenbeek, Belgium. Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. European Inst Oncol, Milan, Italy. Katholieke Univ Leuven, Div Geriatr Med, Dept Internal Med, Louvain, Belgium. Fund Sci Res, Flanders, Belgium.Geusens, P, Limburgs Univ Ctr, Inst Biomed Res, Univ Campus, B-3590 Diepenbeek, Belgium.
URI: http://hdl.handle.net/1942/2628
DOI: 10.1053/apmr.2002.33111
ISI #: 000176600700004
ISSN: 0003-9993
Category: A1
Type: Journal Contribution
Validation: ecoom, 2003
Appears in Collections: Research publications

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