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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/2544

Title: Evolution of recurrent asthma event rate over time in frailty models
Authors: DUCHATEAU, Luc
JANSSEN, Paul
Kezic, I
Fortpied, C
Issue Date: 2003
Publisher: BLACKWELL PUBL LTD
Citation: JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 52. p. 355-363
Abstract: To model the time evolution of the event rate in recurrent event data a crucial role is played by the timescale that is used. Depending on the timescale selected the interpretation of the time evolution will be entirely different, both in parametric and semiparametric frailty models. The gap timescale is more appropriate when studying the recurrent event rate as a function of time since the last event, whereas the calendar timescale keeps track of actual time. We show both timescales in action on data from an asthma prevention trial in young children. The frailty model is further extended to include both timescales simultaneously as this might be most relevant in practice.
Notes: State Univ Ghent, Fac Vet Med, Dept Physiol Biochem & Biometr, B-9820 Merelbeke, Belgium. Limburgs Univ Ctr, Diepenbeek, Belgium. Union Chim Belge, Braine Lalleud, Belgium.Duchateau, L, State Univ Ghent, Fac Vet Med, Dept Physiol Biochem & Biometr, Salisburylaan 133, B-9820 Merelbeke, Belgium.
URI: http://hdl.handle.net/1942/2544
DOI: 10.1111/1467-9876.00409
ISI #: 000184347700007
ISSN: 0035-9254
Category: A1
Type: Journal Contribution
Validation: ecoom, 2004
Appears in Collections: Research publications

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