Document Server@UHasselt >
Research >
Research publications >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/25004

Title: Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
Authors: Spina, Gabriele
Spruit, Martijn A.
Alison, Jennifer
Benzo, Roberto P.
Calverley, Peter M. A.
Clarenbach, Christian F.
Costello, Richard W.
Donaire-Gonzalez, David
Durr, Selina
Garcia-Aymerich, Judith
van Gestel, Arnoldus J. R.
Gramm, Marco
Hernandes, Nidia A.
Hill, Kylie
Hopkinson, Nicholas S.
Jarreta, Diana
Kohler, Malcolm
Kirsten, Anne M.
Leuppi, Jorg D.
Magnussen, Helgo
Maltais, Francois
Man, William D-C
McKeough, Zoe J.
Mesquita, Rafael
Miedinger, David
Pitta, Fabio
Singh, Sally J.
Smeenk, Frank W. J. M.
Tal-Singer, Ruth
Vagaggini, Barbara
Waschki, Benjamin
Watz, Henrik
Wouters, Emiel F. M.
Zogg, Stefanie
den Brinker, Albertus C.
Issue Date: 2017
Citation: THORAX, 72(8), p. 694-701
Abstract: Background Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in daily life have not been investigated before nor has the association between sleep and the ability to engage in physical activity on a day-to-day basis been studied. Aims To provide insight into the relationship between actigraphic sleep measures and disease severity, exertional dyspnoea, gender and parts of the week; and to investigate the association between sleep measures and next day physical activity. Methods Data were analysed from 932 patients with COPD (66% male, 66.4 +/- 8.3 years, FEV1% predicted= 50.8 +/- 20.5). Participants had sleep and physical activity continuously monitored using a multisensor activity monitor for a median of 6 days. Linear mixed effects models were applied to investigate the factors associated with sleep impairment and the association between nocturnal sleep and patients' subsequent daytime physical activity. Results Actigraphic estimates of sleep impairment were greater in patients with worse airflow limitation and worse exertional dyspnoea. Patients with better sleep measures (ie, non-fragmented sleep, sleeping bouts >= 225 min, sleep efficiency >= 91% and time spent awake after sleep onset < 57 min) spent significantly more time in light (p< 0.01) and moderate-to-vigorous physical activity (p< 0.01). Conclusions There is a relationship between measures of sleep in patients with COPD and the amount of activity they undertake during the waking day. Identifying groups with specific sleep characteristics may be useful information when designing physical activity-enhancing interventions.
Notes: [Spina, Gabriele; den Brinker, Albertus C.] Philips Res, Data Sci Grp, High Tech Campus 34, NL-5656 AE Eindhoven, Netherlands. [Spina, Gabriele] Tech Univ Eindhoven, Dept Signal Proc Syst, Eindhoven, Netherlands. [Spruit, Martijn A.; Mesquita, Rafael; Wouters, Emiel F. M.] CIRO, Dept Res & Educ, Ctr Expertise Chron Organ Failure, Horn, Netherlands. [Spruit, Martijn A.] Hasselt Univ, BIOMED Biomed Res Inst, Fac Med & Life Sci, REVAL Rehabil Res Ctr, Diepenbeek, Belgium. [Spruit, Martijn A.] Maastricht Univ, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Med Ctr, Maastricht, Netherlands. [Alison, Jennifer; McKeough, Zoe J.] Univ Sydney, Clin & Rehabil Sci, Sydney, NSW, Australia. [Alison, Jennifer] Royal Prince Alfred Hosp, Physiotherapy Dept, Sydney, NSW, Australia. [Benzo, Roberto P.] Mayo Clin, Mindful Breathing Lab, Rochester, MN USA. [Calverley, Peter M. A.] Aintree Univ Hosp NHS Fdn Trust, Sch Ageing & Chron Dis, Liverpool, Merseyside, England. [Clarenbach, Christian F.; van Gestel, Arnoldus J. R.; Kohler, Malcolm] Univ Hosp Zurich, Div Pulm, Zurich, Switzerland. [Costello, Richard W.] Beaumont Hosp, Dept Resp Med, Dublin, Ireland. [Donaire-Gonzalez, David; Garcia-Aymerich, Judith] Ctr Res Environm Epidemiol CREAL, Barcelona, Spain. [Donaire-Gonzalez, David; Garcia-Aymerich, Judith] CIBERESP, Barcelona, Spain. [Donaire-Gonzalez, David; Garcia-Aymerich, Judith] UPF, Barcelona, Spain. [Durr, Selina; Leuppi, Jorg D.; Miedinger, David; Zogg, Stefanie] Univ Basel, Cantonal Hosp Baselland, Liestal & Med Fac, Med Univ Clin, Basel, Switzerland. [Gramm, Marco; Kirsten, Anne M.; Magnussen, Helgo; Waschki, Benjamin; Watz, Henrik] German Ctr Lung Res, Airway Res Ctr North, Lung Clin Grosshansdorf, Pulm Res Inst, Grosshansdorf, Germany. [Hernandes, Nidia A.; Pitta, Fabio] State Univ Londrina UEL, Dept Physiotherapy, Lab Res Resp Physiotherapy, Londrina, Brazil. [Hill, Kylie] Curtin Univ, Sch Physiotherapy & Exercise Sci, Perth, WA, Australia. [Hopkinson, Nicholas S.; Man, William D-C] Royal Brompton & Harefield NHS Fdn Trust, NIHR Resp Biomed Res Unit, London, England. [Hopkinson, Nicholas S.; Man, William D-C] Imperial Coll, London, England. [Jarreta, Diana] AstraZeneca, Barcelona, Spain. [Maltais, Francois] Univ Laval, Inst Univ Cardiol & Pneumol Quebec, Ctr Rech, 2725 Chemin Ste Foy Quebec, Quebec City, PQ, Canada. [Mesquita, Rafael; Wouters, Emiel F. M.] Maastricht Univ, Med Ctr, Dept Resp Med, Maastricht, Netherlands. [Singh, Sally J.] Univ Hosp Leicester NHS Trust, Ctr Exercise & Rehabil Sci, Leicester, Leics, England. [Smeenk, Frank W. J. M.] Catharina Hosp, Dept Resp Med, Eindhoven, Netherlands. [Tal-Singer, Ruth] GlaxoSmithKline Res & Dev Ltd, King Of Prussia, PA USA. [Vagaggini, Barbara] Univ Pisa, Cardiothorac & Vasc Dept, Pisa, Italy.
URI: http://hdl.handle.net/1942/25004
DOI: 10.1136/thoraxjnl-2016-208900
ISI #: 000405401100008
ISSN: 0040-6376
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

Files in This Item:

Description SizeFormat
Published version1.12 MBAdobe PDF

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.