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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/24213

Title: The Impact of Kidney Development on the Life Course: A Consensus Document for Action The Low Birth Weight and Nephron Number Working Group
Authors: Brenner, Barry M.
Charlton, Jennifer
Luyckx, Valerie
Manfellotto, Dario
Perico, Norberto
Remuzzi, Giuseppe
Somaschini, Marco
Valensise, Herbert
Adu, Dwomoa
Allegaert, Karel
Benedetto, Chiara
Cetin, Irene
Chevalier, Robert
Cortinovis, Monica
D'Anna, Rosario
Duvekot, Johannes
Escribano, Joaquin
Fanos, Vassilios
Ferrazzi, Enrico
Frusca, Tiziana
Glassock, Richard J.
Gyselaers, Wilfried
Mecacci, Federico
Montini, Giovanni
Osmond, Clive
Ramenghi, Luca
Romagnani, Paola
Santoro, Antonio
Simeoni, Umberto
Steegers, Eric A. P.
Vikse, Bjorn Egil
Issue Date: 2017
Publisher: KARGER
Citation: NEPHRON, 136(1), p. 3-49
Abstract: Hypertension and chronic kidney disease (CKD) have a significant impact on global morbidity and mortality. The Low Birth Weight and Nephron Number Working Group has prepared a consensus document aimed to address the relatively neglected issue for the developmental programming of hypertension and CKD. It emerged from a workshop held on April 2, 2016, including eminent internationally recognized experts in the field of obstetrics, neonatology, and nephrology. Through multidisciplinary engagement, the goal of the workshop was to highlight the association between fetal and childhood development and an increased risk of adult diseases, focusing on hypertension and CKD, and to suggest possible practical solutions for the future. The recommendations for action of the consensus workshop are the results of combined clinical experience, shared research expertise, and a review of the literature. They highlight the need to act early to prevent CKD and other related noncommunicable diseases later in life by reducing low birth weight, small for gestational age, prematurity, and low nephron numbers at birth through coordinated interventions. Meeting the current unmet needs would help to define the most cost-effective strategies and to optimize interventions to limit or interrupt the developmental programming cycle of CKD later in life, especially in the poorest part of the world. (C) 2017 The Author(s) Published by S. Karger AG, Basel
Notes: [Remuzzi, Giuseppe] IRCCS Ist Ric Farmacol Mario Negri, Ctr Anna Maria Astori, Sci & Techno Pk Kilometro Rosso Via Stezzano 87, Bergamo, Italy. [Brenner, Barry M.] Harvard Med Sch, Boston, MA USA. [Brenner, Barry M.] Brigham & Womens Hosp, Div Renal, Boston, MA 02115 USA. [Charlton, Jennifer] Univ Virginia, Childrens Hosp, Dept Pediat, Div Nephrol, Charlottesville, VA USA. [Luyckx, Valerie] Univ Zurich, Inst Biomed Eth, Zurich, Switzerland. [Manfellotto, Dario] San Giovanni Calibita Fatebenefratelli Hosp, Fatebenefratelli Fdn, Dept Internal Med, AFaR Div, Rome, Italy. [Perico, Norberto; Remuzzi, Giuseppe; Cortinovis, Monica] IRCCS Ist Ric Farmacol Mario Negri, Clin Res Ctr Rare Dis Aldo & Cele Dacca, Bergamo, Italy. [Remuzzi, Giuseppe] Azienda Socio Sanitaria Terr ASST Papa Giovanni X, Unit Nephrol Dialysis & Transplantat, Bergamo, Italy. [Remuzzi, Giuseppe] Univ Milan, Hosp L Sacco, Dept Biomed & Clin Sci, Milan, Italy. [Somaschini, Marco] St Anna Clin, Unit Neonatol, Lugano, Switzerland. [Valensise, Herbert] Tor Vergata Univ, Dept Obstet & Gynecol, Rome, Italy. [Adu, Dwomoa] Univ Ghana, Sch Med & Dent, Accra, Ghana. [Allegaert, Karel] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Pediat Surg, Rotterdam, Netherlands. [Allegaert, Karel] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Intens Care, Rotterdam, Netherlands. [Allegaert, Karel] Katholieke Univ Leuven, Dept Dev & Regenerat, Leuven, Belgium. [Benedetto, Chiara] Univ Turin, Dept Surg Sci, Unit Gynecol & Obstet, Turin, Italy. [Cetin, Irene] Hosp L Sacco, Dept Biomed & Clin Sci, Unit Obstet & Gynecol, Milan, Italy. [Cetin, Irene] Univ Milan, Ctr Fetal Res Giorgio Pardi, Milan, Italy. [Chevalier, Robert] Univ Virginia, Charlottesville, VA USA. [D'Anna, Rosario] Univ Messina, Dept Human Pathol Adulthood & Childhood G Barresi, Unit Gynecol & Obstet, Messina, Italy. [Duvekot, Johannes] Erasmus MC, Dept Obstet & Gynecol, Div Obstet & Prenatal Med, Rotterdam, Netherlands. [Escribano, Joaquin] Univ Rovira & Virgili, IISPV, Pediat Res Unit, Reus, Spain. [Fanos, Vassilios] Univ Cagliari, Azienda Osped Univ, Neonatal Intens Care Unit, Puericulture Inst & Neonatal Sect, Cagliari, Italy. [Ferrazzi, Enrico] Univ Milan, ICP Buzzi Childrens Hosp, Sch Med, Dept Obstet Gynecol & Neonatol,Biomed & Clin Sci, Milan, Italy. [Frusca, Tiziana] Univ Parma, Maggiore Hosp, Dept Obstet & Gynecol, Parma, Italy. [Glassock, Richard J.] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Laguna Niguel, CA USA. [Gyselaers, Wilfried] Hasselt Univ, Fac Med & Life Sci, Dept Physiol, Mobile Hlth Unit, Hasselt, Belgium. [Gyselaers, Wilfried] Ziekenhuis Oost Limburg, Dept Gynecol, Genk, Belgium. [Mecacci, Federico] Univ Florence, Careggi Univ Hosp, Dept Biomed Expt & Clin Sci, Div Obstet & Gynecol, Florence, Italy. [Montini, Giovanni] Univ Milan, Osped Maggiore Policlin, Fdn IRCCS Ca Granda, Dept Clin Sci & Community Hlth,Pediat Nephrol & D, Milan, Italy. [Osmond, Clive] Univ Southampton, Southampton Gen Hosp, MRC Lifecourse Epidemiol Unit, Southampton, Hants, England. [Ramenghi, Luca] Ist Giannina Gaslini, Neonatal Intens Care Unit, Genoa, Italy. [Romagnani, Paola] Univ Florence, Excellence Ctr Res Transfer & High Educ Dev Novo, Florence, Italy. [Romagnani, Paola] Univ Florence, Dept Biomed Exp & Clin Sci, Florence, Italy. [Romagnani, Paola] Meyer Childrens Univ Hosp, Nephrol Unit, Florence, Italy. [Santoro, Antonio] St Orsola Marcello Malpighi Hosp, Dept Nephrol & Dialysis, Bologna, Italy. [Simeoni, Umberto] Univ Lausanne, Serv Pediat, Lausanne, Switzerland. [Steegers, Eric A. P.] Erasmus Univ, Med Ctr Rotterdam, Dept Obstet & Gynecol, Div Obstet & Prenatal Med, Rotterdam, Netherlands. [Vikse, Bjorn Egil] Haugesund Hosp, Dept Med, Haugesund, Norway. [Vikse, Bjorn Egil] Univ Bergen, Dept Clin Med, Bergen, Norway.
URI: http://hdl.handle.net/1942/24213
DOI: 10.1159/000457967
ISI #: 000400723700002
ISSN: 1660-8151
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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