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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/23994

Title: The European Hematology Association Roadmap for European Hematology Research: a consensus document
Authors: Engert, Andreas
Balduini, Carlo
Brand, Anneke
Coiffier, Bertrand
Cordonnier, Catherine
Doehner, Hartmut
de Wit, Thom Duyvene
Eichinger, Sabine
Fibbe, Willem
Green, Tony
de Haas, Fleur
Iolascon, Achille
Jaffredo, Thierry
Rodeghiero, Francesco
Salles, Gilles
Schuringa, Jan Jacob
Andre, Marc
Andre-Schmutz, Isabelle
Bacigalupo, Andrea
Bochud, Pierre-Yves
den Boer, Monique
Bonini, Chiara
Camaschella, Clara
Cant, Andrew
Cappellini, Maria Domenica
Cazzola, Mario
Lo Celso, Cristina
Dimopoulos, Meletios
Douay, Luc
Dzierzak, Elaine
Einsele, Hermann
Ferreri, Andres
De Franceschi, Lucia
Gaulard, Philippe
Gottgens, Berthold
Greinacher, Andreas
Gresele, Paolo
Gribben, John
de Haan, Gerald
Hansen, John-Bjarne
Hochhaus, Andreas
Kadir, Rezan
Kaveri, Srini
Kouskoff, Valerie
Kuehne, Thomas
Kyrle, Paul
Ljungman, Per
Maschmeyer, Georg
Mendez-Ferrer, Simon
Milsom, Michael
Mummery, Christine
Ossenkoppele, Gert
Pecci, Alessandro
Peyvandi, Flora
Philipsen, Sjaak
Reitsma, Pieter
Maria Ribera, Jose
Risitano, Antonio
Rivella, Stefano
Ruf, Wolfram
Schroeder, Timm
Scully, Marie
Socie, Gerard
Staal, Frank
Stanworth, Simon
Stauder, Reinhard
Stilgenbauer, Stephan
Tamary, Hannah
Theilgaard-Monch, Kim
Thein, Swee Lay
Tilly, Herve
Trneny, Marek
Vainchenker, William
Vannucchi, Alessandro Maria
Viscoli, Claudio
Vrielink, Hans
Zaaijer, Hans
Zanella, Alberto
Zolla, Lello
Zwaginga, Jaap Jan
Martinez, Patricia Aguilar
van den Akker, Emile
Allard, Shubha
Anagnou, Nicholas
Andolfo, Immacolata
Andrau, Jean-Christophe
Angelucci, Emanuele
Anstee, David
Aurer, Igor
Avet-Loiseau, Herve
Aydinok, Yesim
Bakchoul, Tamam
Balduini, Alessandra
Barcellini, Wilma
Baruch, Dominique
Baruchel, Andre
Bayry, Jagadeesh
Bento, Celeste
van den Berg, Anke
Bernardi, Rosa
Bianchi, Paola
Bigas, Anna
Biondi, Andrea
Bohonek, Milos
Bonnet, Dominique
Borchmann, Peter
Borregaard, Niels
Braekkan, Sigrid
van den Brink, Marcel
Brodin, Ellen
Bullinger, Lars
Buske, Christian
Butzeck, Barbara
Cammenga, Jorg
Campo, Elias
Carbone, Antonino
Cervantes, Francisco
Cesaro, Simone
Charbord, Pierre
Claas, Frans
Cohen, Hannah
Conard, Jacqueline
Coppo, Paul
Vives Corrons, Joan-Lluis
da Costa, Lydie
Davi, Frederic
Delwel, Ruud
Dianzani, Irma
Domanovic, Dragoslav
Donnelly, Peter
Drnovsek, Tadeja Dovc
Dreyling, Martin
Du, Ming-Qing
Dufour, Carlo
Durand, Charles
Efremov, Dimitar
Eleftheriou, Androulla
Elion, Jacques
Emonts, Marieke
Engelhardt, Monika
Ezine, Sophie
Falkenburg, Fred
Favier, Remi
Federico, Massimo
Fenaux, Pierre
Fitzgibbon, Jude
Flygare, Johan
Foa, Robin
Forrester, Lesley
Galacteros, Frederic
Garagiola, Isabella
Gardiner, Chris
Garraud, Olivier
van Geet, Christel
Geiger, Hartmut
Geissler, Jan
Germing, Ulrich
Ghevaert, Cedric
Girelli, Domenico
Godeau, Bertrand
Goekbuget, Nicola
Goldschmidt, Hartmut
Goodeve, Anne
Graf, Thomas
Graziadei, Giovanna
Griesshammer, Martin
Gruel, Yves
Guilhot, Francois
von Gunten, Stephan
Gyssens, Inge
Halter, Jorg
Harrison, Claire
Harteveld, Cornelis
Hellstrom-Lindberg, Eva
Hermine, Olivier
Higgs, Douglas
Hillmen, Peter
Hirsch, Hans
Hoskin, Peter
Huls, Gerwin
Inati, Adlette
Johnson, Peter
Kattamis, Antonis
Kiefel, Volker
Kleanthous, Marina
Klump, Hannes
Krause, Daniela
Hovinga, Johanna Kremer
Lacaud, Georges
Lacroix-Desmazes, Sebastien
Landman-Parker, Judith
LeGouill, Steven
Lenz, Georg
von Lilienfeld-Toal, Marie
von Lindern, Marieke
Lopez-Guillermo, Armando
Lopriore, Enrico
Lozano, Miguel
MacIntyre, Elizabeth
Makris, Michael
Mannhalter, Christine
Martens, Joost
Mathas, Stephan
Matzdorff, Axel
Medvinsky, Alexander
Menendez, Pablo
Migliaccio, Anna Rita
Miharada, Kenichi
Mikulska, Malgorzata
Minard, Veronique
Montalban, Carlos
de Montalembert, Mariane
Montserrat, Emili
Morange, Pierre-Emmanuel
Mountford, Joanne
Muckenthaler, Martina
Mueller-Tidow, Carsten
Mumford, Andrew
Nadel, Bertrand
Navarro, Jose-Tomas
el Nemer, Wassim
Noizat-Pirenne, France
O'Mahony, Brian
Oldenburg, Johannes
Olsson, Martin
Oostendorp, Robert
Palumbo, Antonio
Passamonti, Francesco
Patient, Roger
de Latour, Regis Peffault
Pflumio, Francoise
Pierelli, Luca
Piga, Antonio
Pollard, Debra
Raaijmakers, Marc
Radford, John
Rambach, Ralf
Rao, A. Koneti
Raslova, Hana
Rebulla, Paolo
Rees, David
Ribrag, Vincent
Rijneveld, Anita
Rinalducci, Sara
Robak, Tadeusz
Roberts, Irene
Rodrigues, Charlene
Rosendaal, Frits
Rosenwald, Andreas
Rule, Simon
Russo, Roberta
Saglio, Guiseppe
Sanchez, Mayka
Scharf, Ruediger E.
Schlenke, Peter
Semple, John
Sierra, Jorge
So-Osman, Cynthia
Manuel Soria, Jose
Stamatopoulos, Kostas
Stegmayr, Bernd
Stunnenberg, Henk
Swinkels, Dorine
Taborda Barata, Joao Pedro
Taghon, Tom
Taher, Ali
Terpos, Evangelos
Thachil, Jecko
Tissot, Jean Daniel
Touw, Ivo
Toye, Ash
Trappe, Ralf
Traverse-Glehen, Alexandra
Unal, Sule
Vaulont, Sophie
Viprakasit, Vip
Vitolo, Umberto
van Wijk, Richard
Wojtowicz, Agnieszka
Zeerleder, Sacha
Zieger, Barbara
Issue Date: 2016
Citation: HAEMATOLOGICA, 101(2), p. 115-208
Abstract: The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine ‘sections’ in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.
URI: http://hdl.handle.net/1942/23994
DOI: 10.3324/haematol.2015.136739
ISI #: 000379156300012
ISSN: 0390-6078
Category: A1
Type: Journal Contribution
Validation: ecoom, 2017
Appears in Collections: Research publications

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