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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/23756

Title: Junctional zone thickness in young nulliparous women according to menstrual cycle and hormonal contraception use
Authors: Meylaerts, Liesbeth Johannes
Wijnen, Leen
Grieten, Martijn
Palmers, Yvan
Ombelet, Willem
Vandersteen, Marjan
Issue Date: 2017
Citation: REPRODUCTIVE BIOMEDICINE ONLINE, 34(2), p. 212-220
Abstract: This prospective study aims to determine the optimal menstrual phase and uterine location to detect the thickest junctional zone by magnetic resonance imaging (MRI). Healthy nulliparous women were subdivided according to their use of hormonal contraception. Each women was investigated three times during their menstrual cycle. Eighteen nulliparous non-users and 29 nulliparous users of hormonal contraception (mean age 26.4 and 25.8 years, respectively) underwent a pelvic MRI (1.5T) examination during the follicular, ovulatory and luteal phase. The junctional zone thickness was measured at six locations in the uterine wall. A significantly thinner junctional zone was observed at the anterior and posterior wall of the midcorpus (P = 0.01 and P = 0.004 respectively) and fundus (P = 0.009 and P = 0.023 respectively), in the contraception users compared with the non-users. No differences in junctional zone thickness were noticed between the menstrual phases and the uterine wall locations. The ratio of junctional zone versus total myometrial thickness was also different between both groups and between the assessed uterine locations. To conclude, any phase in the menstrual cycle and location within the uterine wall was validated to determine the junctional zone thickness on MRI, although the fundal location is preferred.
Notes: [Meylaerts, Liesbeth Johannes; Wijnen, Leen; Grieten, Martijn; Palmers, Yvan] Ziekenhuis Oost Limburg, Dept Med Imaging, Schiepsebos 6, B-3600 Genk, Belgium. [Ombelet, Willem] Ziekenhuis Oost Limburg, Dept Ostetr & Gynaecol, Schiepsebos 6, B-3600 Genk, Belgium. [Vandersteen, Marjan] Univ Hasselt, Fac Med & Biomed, Campus Diepenbeek, B-3590 Diepenbeek, Belgium.
URI: http://hdl.handle.net/1942/23756
DOI: 10.1016/j.rbmo.2016.10.013
ISI #: 000393171200016
ISSN: 1472-6483
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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