www.uhasselt.be
DSpace

Document Server@UHasselt >
Research >
Research publications >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/2334

Title: Biochemical markers of joint tissue turnover in early rheumatoid arthritis
Authors: Garnero, P
GEUSENS, Piet
Landewe, R
Issue Date: 2003
Publisher: CLINICAL & EXPER RHEUMATOLOGY
Citation: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 21(5). p. S54-S58
Abstract: The progression of rheumatoid arthritis (RA), a disease characterized by synovitis, cartilage degradation and bone erosion, is highly variable from patient to patient. New specific biological markers reflecting quantitative and dynamic changes in joint tissue turnover have been recently developed and include assays for type II collagen synthesis and degradation and synovitis. Increasing evidence from prospective studies in early RA indicate that some of these markers may be useful to predict the progression and identify patients at risk for rapid joint damage, before any damage is detected by radiography. Although studies on their value in assessing the efficacy of treatments are still limited, preliminary data in early RA suggest that biological markers will play an important role in the development and the early monitoring of disease modifying antirheumatic drugs with respect to future radiographic progression.
Notes: Synarc, Mol Markers, F-69003 Lyon, France. State Univ Limburg Hosp, NL-6201 BX Maastricht, Netherlands. Univ Diepenbeek, Dr Willems Inst, Diepenbeek, Belgium.Garnero, P, Synarc, Mol Markers, 16 Rue Montbrillant, F-69003 Lyon, France.
URI: http://hdl.handle.net/1942/2334
ISI #: 000185970100010
ISSN: 0392-856X
Category: A1
Type: Journal Contribution
Validation: ecoom, 2004
Appears in Collections: Research publications

Files in This Item:

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.