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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/23115

Title: Introducing copper-free 'Click' amino acids into the VCAM-1 targeting Nanobody for advanced medical biomaterials
Authors: Hansen, Rebekka
Smeets, Sofie
Adriaensens, Peter
Guedens, Wanda
Issue Date: 2016
Citation: Biodetection & Biosensors 2016, Cambridge, UK, 18-19/10/2016
Abstract: The goal of this project is to site-specifically functionalize nanobodies with a copper-free ‘click’ functionality, to allow an oriented and covalent coupling to a complementary functionalized surface. A methodology is proposed in which an unnatural amino acid is introduced in the protein structure, with applications towards biosensor chips and affinity-based chromatography.
URI: http://hdl.handle.net/1942/23115
Category: C2
Type: Conference Material
Appears in Collections: Research publications

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