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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/23058

Title: Biocidal Inactivation of Lactococcus lactis Bacteriophages: Efficacy and Targets of Commonly Used Sanitizers
Authors: Hayes, Stephen
Murphy, James
Mahony, Jennifer
Lugli, Gabriele
Ventura, Marco
Noben, Jean-Paul
Franz, Charles
Neve, Horst
Nauta, Arjen
Van Sinderen, Douwe
Issue Date: 2017
Citation: Frontiers in Microbiology, 8 (Art N° 107)
Abstract: Lactococcus lactis strains, being intensely used in the dairy industry, are particularly vulnerable to members of the so-called 936 group of phages. Sanitization and disinfection using purpose-made biocidal solutions is a critical step in controlling phage contamination in such dairy processing plants. The susceptibility of 36 936 group phages to biocidal treatments was examined using 14 biocides and commercially available sanitizers. The targets of a number of these biocides were investigated by means of electron microscopic and proteomic analyses. The results from this study highlight significant variations in phage resistance to biocides among 936 phages. Furthermore, rather than possessing resistance to specific biocides or biocide types, biocide-resistant phages tend to possess a broad tolerance to multiple classes of antimicrobial compounds.
Notes: d.vansinderen@ucc.ie
URI: http://hdl.handle.net/1942/23058
DOI: 10.3389/fmicb.2017.00107
ISI #: 000393135600001
ISSN: 1664-302X
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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