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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/22604

Title: Cone-beam CT to assess bony fusion following anterior cervical interbody fusion
Authors: Vandevenne, Jan
Peuskens, Dieter
Wijnen, Leen
Wuyts, Jan
Issue Date: 2016
Publisher: SPRINGER
Citation: EUROPEAN SPINE JOURNAL, 25(S1), p. S134-S139
Abstract: Purpose Assessment of bony fusion following anterior cervical interbody fusion (ACIF) is usually done by plain film or CT. We present the first clinical application of Cone-Beam CT (CBCT) to evaluate bony fusion after ACIF. Methods A 56-year-old man with disc herniation at C6-C7 underwent ACIF surgery using a compressed nanocrystalline hydroxyapatite interbody device (nanOss-C, Pioneer Surgical Marquette, MI, USA) and a nanocrystalline hydroxyapatite bone graft filler (nanOss Bioactive, Pioneer Surgical Marquette, MI, USA). Imaging follow-up was performed by CBCT (NewTom 5G, QR Srl, Verona, Italy) at 1 day, 6 weeks, 3 and 9 months post-operatively. Two independent assessors quantitatively measured the greyscale changes of the bone graft filler and qualitatively evaluated the bony fusion process. Results Quantitative analysis of the images showed a steadily increasing matrix density of the bone graft filler over the 9 months follow-up, suggesting increasing calcification. Qualitative evaluation demonstrated different stages of the bone fusion process within the disc space around the cage, at the interface between cage and end-plates, and at the interface between bone graft filler and the endplates. Conclusions CBCT provides high-resolution cross-sectional imaging of the cervical spine after ACIF. For the first time, in vivo evaluation of the bone graft filler within the centre of the circumferentially radiodense cage and detailed cross-sectional evaluation of bone fusion was achieved. Confirmation of these promising outlooks of CBCT in a large cohort of ACIF patients is needed with regard to routine clinical application and evaluation of different interbody devices.
Notes: [Vandevenne, Jan Erik; Wijnen, Leen] Univ Hasselt, Fac Med, Hasselt, Belgium. [Vandevenne, Jan Erik] Ziekenhuis Oost Limburg, Dept Radiol, Campus St Jan,Schiepse Bos 6, B-3600 Genk, Belgium. [Peuskens, Dieter; Wuyts, Jan] Ziekenhuis Oost Limburg, Dept Neurosurg, Campus St Jan,Schiepse Bos 6, B-3600 Genk, Belgium.
URI: http://hdl.handle.net/1942/22604
DOI: 10.1007/s00586-015-4248-8
ISI #: 000382701100024
ISSN: 0940-6719
Category: A1
Type: Journal Contribution
Validation: ecoom, 2017
Appears in Collections: Research publications

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