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|Title: ||Impact of high-intensity exercise on endurance capacity and muscle strength in persons with multiple sclerosis|
|Authors: ||Zeelmaekers, Kimberly|
|Advisors: ||OP 'T EIJNDE, Bert|
|Issue Date: ||2016|
|Abstract: ||Background: Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by progressive demyelination of the central nervous system. The heterogeneous symptoms, such as deterioration of muscle strength and endurance capacity, lead to a predisposition of a sedentary lifestyle. To diminish these symptoms, exercise therapy is indicated, preferably a combined strength and endurance training program. However, research tends to focus on low-to-moderate intensities and only one study demonstrates the effects of a combined high intensity exercise program.
Objectives: To determine whether a 12-week combined high intensity interval program has an impact on muscle strength, endurance capacity and body composition in people with MS.
Participants: Thirty-one people with MS were selected based on inclusion and exclusion criteria and divided into an experimental or control group.
Measurements: Exercise capacity and muscle strength were considered as primary outcome measures, whilst body composition was considered as a secondary outcome measure.
Results: After 12 weeks of training workload, VO2max, mean ventilatory exchange (VE) and muscle strength improved in the intervention group, especially for the weakest leg. In contrast, the control group remained stable or deteriorated over time. No changes in body composition were detected in both groups.
Conclusion: People with MS benefit from a 12-week combined high intensity exercise program, concerning exercise capacity and muscle strength compared to usual care.|
|Notes: ||master in de revalidatiewetenschappen en de kinesitherapie-revalidatiewetenschappen en kinesitherapie bij kinderen|
|Type: ||Theses and Dissertations|
|Appears in Collections: ||Master theses|
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