Document Server@UHasselt >
Research >
Research publications >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/21618

Title: Palliative endovascular treatment of cancer-related iliocaval obstructive disease: technical and clinical outcomes
Authors: Maleux, Geert
Vertenten, Bart
Laenen, Annouschka
De Wever, Liesbeth
Heye, Sam
Clement, Paul
Oyen, Raymond
Issue Date: 2016
Citation: ACTA RADIOLOGICA, 57 (4), p. 451-456
Abstract: Background Cancer-related obstruction of large abdominal and pelvic veins might become symptomatic with clinical signs of lower limb venous congestion. Technical and clinical outcome after interventional treatment is not well studied yet. Purpose To retrospectively assess the technical and clinical outcome of endovascular management of symptomatic cancer-related iliocaval venous obstructive disease. Material and Methods From 1998 to 2013, 19 patients (15 men, 4 women; mean age, 63.6 years) referred for interventional treatment of cancer-related iliocaval obstructive disease were identified. Patients' symptoms included unilateral (n=16; 84%) or bilateral (n=3; 16%) painful swelling of the lower limbs. Patients' demographics as well as interventional and clinical outcome data were collected. Results All 19 patients underwent, under local anesthesia, stenting of the iliac vein (n=16; 84%) or inferior vena cava (n=3; 16%). Immediate technical success (n=19) was 100%; immediate clinical success (n=18) was 94.7%. During follow-up, seven patients (36.8%) presented with recurrent symptoms of painful limb swelling. Estimated survival after 3 and 6 months was 68.4% (95% confidence interval [CI], 47.8-82.3%) and 19.8% (95% CI, 11.9-29.2%), respectively. Conclusion Endovascular stenting of cancer-related iliocaval venous obstructive disease is safe and results in immediate relief of symptoms. However, recurrent venous obstruction is common. At 3 months follow-up, the majority of patients with iliac vein stenting were still alive.
Notes: [Maleux, Geert; Vertenten, Bart; De Wever, Liesbeth; Heye, Sam; Oyen, Raymond] Katholieke Univ Leuven, Dept Imaging & Pathol, Univ Hosp Leuven, Dept Radiol, Louvain, Belgium. [Laenen, Annouschka] Katholieke Univ Leuven, Interuniv Inst Biostat & Stat Bioinformat, Leuven, Belgium. [Laenen, Annouschka] Univ Hasselt, Leuven, Belgium. [Clement, Paul] Univ Hosp Leuven, Dept Gen Oncol, B-3000 Louvain, Belgium.
URI: http://hdl.handle.net/1942/21618
DOI: 10.1177/0284185115582059
ISI #: 000372811600013
ISSN: 0284-1851
Category: A1
Type: Journal Contribution
Validation: ecoom, 2017
Appears in Collections: Research publications

Files in This Item:

Description SizeFormat
published version318.91 kBAdobe PDF

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.