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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/20623

Authors: Genbrugge, Cornelia
Dens, Jo
Meex, Ingrid
Boer, Willem
Eertmans, Ward
Sabbe, Marc
Jans, Frank
De Deyne, Cathy
Issue Date: 2016
Citation: JOURNAL OF EMERGENCY MEDICINE, 50 (1), p. 198-207
Abstract: Background: Approximately 375,000 people annually experience sudden cardiac arrest (CA) in Europe. Most patients who survive the initial hours and days after CA die of postanoxic brain damage. Current monitors, such as electrocardiography and end-tidal capnography, provide only indirect information about the condition of the brain during cardiopulmonary resuscitation (CPR). In contrast, cerebral near-infrared spectroscopy provides continuous, noninvasive, real-time information about brain oxygenation without the need for a pulsatile blood flow. It measures transcutaneous cerebral tissue oxygen saturation (rSO(2)). This information could supplement currently used monitors. Moreover, an evolution in rSO(2) monitoring technology has made it easier to assess rSO(2) in CA conditions. Objective: We give an overview of the literature regarding rSO(2) measurements during CPR and the current commercially available devices. We highlight the feasibility of cerebral saturation measurement during CPR, its role as a quality parameter of CPR, predictor of return of spontaneous circulation (ROSC) and neurologic outcome, and its monitoring function during transport. Discussion: rSO(2) is feasible in the setting of CA and has the potential to measure the quality of CPR, predict ROSC and neurologic outcome, and monitor post-CA patients during transport. Conclusion: The literature shows that rSO(2) has the potential to serve multiple roles as a neuromonitoring tool during CPR and also to guide neuroprotective therapeutic strategies. (C) 2016 Elsevier Inc.
Notes: [Genbrugge, Cornelia; Meex, Ingrid; Boer, Willem; Eertmans, Ward; Jans, Frank; De Deyne, Cathy] Ziekenhuis Oost Limburg, Dept Anaesthesiol Intens Care Emergency Med & Pai, B-3600 Genk, Belgium. [Genbrugge, Cornelia; Dens, Jo; Meex, Ingrid; Eertmans, Ward; Jans, Frank; De Deyne, Cathy] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. [Dens, Jo] Ziekenhuis Oost Limburg, Dept Cardiol, B-3600 Genk, Belgium. [Sabbe, Marc] Univ Hosp Leuven, Emergency Dept, Leuven, Belgium.
URI: http://hdl.handle.net/1942/20623
DOI: 10.1016/j.jemermed.2015.03.043
ISI #: 000367095000050
ISSN: 0736-4679
Category: A1
Type: Journal Contribution
Validation: ecoom, 2017
Appears in Collections: Research publications

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