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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/19831

Title: Type-specific orthostatic hemodynamic response of hypertensive diseases in pregnancy
Authors: Staelens, Anneleen
Vonck, Sharona
Mesens, Tinne
Tomsin, Kathleen
Molenberghs, Geert
Gyselaers, Wilfried
Issue Date: 2015
Abstract: Posture changes may differ between types of hypertensive disease. The aim is to evaluate the orthostatic response of impedance cardiography (ICG) measurements in uncomplicated and hypertensive pregnancies. Measurements were performed in supine and standing position in 202 women: 41 uncomplicated pregnancies (UP), 59 gestational hypertension (GH), 35 early-onset (EPE, < 34 weeks) and 67 late-onset (LPE, >= 34 weeks) preeclampsia were assessed. Measurements were recorded of heart rate, blood pressure, aortic flow parameters, cardiac output, pre-ejection period and left ventricular ejection time. Overall, orthostatic shifts were different between all groups (P < 0.001). UP was different from the hypertensive complicated gestations in the orthostatic change of the aortic acceleration. In contrast to patients with preeclampsia, those with GH had an increased blood pressure and Heather index, and stable pre-ejection period after posture change. EPE differed from LPE by change in blood pressure and aortic flow parameters. In addition to static ICG-measurements, orthostatic shifts improved group characterization from 57.4% to 65.8%. The orthostatic response is altered in hypertensive pregnancies. ICG measurements in the upright as well as during an orthostatic test might have the potential to improve the discriminative yield between hypertensive diseases in pregnancy.
Notes: [Staelens, Anneleen S.; Vonck, Sharona; Mesens, Tinne; Gyselaers, Wilfried] Ziekenhuis Oost Limburg, Dept Obstet & Gynaecol, B-3600 Genk, Belgium. [Staelens, Anneleen S.; Vonck, Sharona; Tomsin, Kathleen] Hasselt Univ, Dept Med & Life Sci, Hasselt, Belgium. [Molenberghs, Geert] Hasselt Univ, I BioStat, Hasselt, Belgium. [Molenberghs, Geert] Univ Leuven, I BioStat, Leuven, Belgium. [Gyselaers, Wilfried] Hasselt Univ, Dept Physiol, Hasselt, Belgium.
URI: http://hdl.handle.net/1942/19831
DOI: 10.1111/1440-1681.12463
ISI #: 000362644300004
ISSN: 1440-1681
Category: A1
Type: Journal Contribution
Validation: ecoom, 2016
Appears in Collections: Research publications

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