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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/18439

Title: Unilateral and bilateral upper limb dysfunction at body functions, activity and participation levels in people with multiple sclerosis.
Authors: Bertoni, Rita
Lamers, Ilse
Chen, Christine C.
Feys Peter
Cattaneo, Davide
Issue Date: 2015
Citation: Multiple Sclerosis Journal, 21 (12), p. 1566-1574
Abstract: BACKGROUND: There has been limited research on upper limb dysfunction in people with multiple sclerosis (PwMS). OBJECTIVE: The objective of this paper is to study unilateral and bilateral upper limb dysfunction at different International Classification of Functioning (ICF) levels according to overall disability in PwMS. METHODS: A total of 105 PwMS (16 with EDSS<4 (mild); 17 with EDSS 4-5.5 (moderate); 37 with EDSS 6-6.5 (severe); 35 with EDSS>6.5 (severe non-ambulant)) were recruited from two rehabilitation centers and assessed in a cross-sectional study. RESULTS: The whole sample showed a diminished sensory function (median (first/third interquartile)) score of 3 (2/3) on the Monofilament Test and a reduced strength 91 (76/100) points on the Motricity Index (Body-Function level). Sensory dysfunction did not increase with higher EDSS while strength decreased from 100 (86/100) in the mild subgroups to 91 (80/100) points in the severe subgroup. All showed diminished dexterity, scoring 0.28 peg/s (0.17/0.35) on the Nine-Hole Peg Test (NHPT) (activity level). Score was better for the mild (0.38 (0.35/0.46)) peg/s compared to the severe subgroup (0.28 (0.17/0.35)). Sixty-eight percent, 44% and 75% of PwMS showed bilateral disorders in sensation, strength and dexterity, respectively. The Community Integration Questionnaire (participation level) showed a 35% reduction in home activities, even among PwMS with EDSS<4. CONCLUSION: This study showed uni-/bilateral upper limb abnormalities at all ICF levels increasing with the overall disability.
Notes: Correspondence to: Davide Cattaneo LaRiCE, Servizio riabilitazione neurologica adulti (Int. 282), Don Gnocchi Foundation, I.R.C.C.S., V. Capecelatro 66 – 20148 Milan, Italy. dcattaneo@dongnocchi.it
URI: http://hdl.handle.net/1942/18439
Link to publication: http://msj.sagepub.com/content/early/2015/01/29/1352458514567553.long
DOI: 10.1177/1352458514567553
ISI #: 000362529200010
ISSN: 1352-4585
Category: A1
Type: Journal Contribution
Validation: ecoom, 2016
Appears in Collections: Research publications

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