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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/17786

Title: Mixed outcomes
Authors: Molenberghs, Geert
Geys, Helena
Issue Date: 2012
Publisher: John Wiley & Sons Ltd
Citation: El-Shaarawi, Abdel H.; Piegorsch, Walter W. (Ed.). Encyclopedia of Environmetrics, p. 1618-1621
Abstract: Measurements of both continuous and discrete outcomes are encountered in many statistical problems. A common example is a developmental toxicity study, which typically involves exposing timepregnant animals (rats, mice) to an environmental agent during major organogenesis. The dams are sacrificed prior to normal delivery, at which time the uterus is removed and thoroughly examined. Among viable fetuses, the incidence of any malformation (binary data) and reductions in fetal weight (continuous data) are typically of primary concern, since both have been found to be sensitive indicators of a toxic effect. This motivates the formulation of a joint distribution with mixed continuous and discrete outcomes.
URI: http://hdl.handle.net/1942/17786
DOI: 10.1002/9780470057339.vam025.pub2
ISBN: 9780470973882
Category: B2
Type: Book Section
Appears in Collections: Research publications

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