www.uhasselt.be
DSpace

Document Server@UHasselt >
Research >
Research publications >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/17201

Title: Ethical issues raised by whole genome sequencing
Authors: PINXTEN, Wim
Howard, Heidi Carmen
Issue Date: 2014
Publisher: ELSEVIER SCI LTD
Citation: BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY, 28 (2), p. 269-279
Abstract: While there is ongoing discussion about the details of implementation of whole genome sequencing (WGS) and whole exome sequencing (WES), there appears to be a consensus amongst geneticists that the widespread use of these approaches is not only inevitable, but will also be beneficial [1]. However, at the present time, we are unable to anticipate the full range of uses, consequences and impact of implementing WGS and WES. Nevertheless, the already known ethical issues, both in research and in clinical practice are diverse and complex and should be addressed properly presently. Herein, we discuss the ethical aspects of WGS and WES by particularly focussing on three overlapping themes: (1) informed consent, (2) data handling, and (3) the return of results. (C) 2014 Elsevier Ltd. All rights reserved.
Notes: [Pinxten, Wim] Hasselt Univ, Fac Med & Life Sci, B-3500 Hasselt, Belgium. [Howard, Heidi Carmen] Radboud Univ Nijmegen, Med Ctr, IQhealthcare, NL-6500 NB Nijmegen, Netherlands. [Howard, Heidi Carmen] Uppsala Univ, Ctr Res Eth & Bioeth, SE-75122 Uppsala, Sweden. wim.pinxten@uhasselt.be; heidi.howard@mail.mcgill.ca
URI: http://hdl.handle.net/1942/17201
DOI: 10.1016/j.bpg.2014.02.004
ISI #: 000336705600006
ISSN: 1521-6918
Category: A1
Type: Journal Contribution
Validation: ecoom, 2015
Appears in Collections: Research publications

Files in This Item:

Description SizeFormat
published version238.85 kBAdobe PDF

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.