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|Title: ||Within-day variability on short and long walking tests in persons with multiple sclerosis|
|Authors: ||FEYS, Peter|
de Noordhout, Benoit Maertens
de Groot, Vincent
|Issue Date: ||2014|
|Citation: ||JOURNAL OF THE NEUROLOGICAL SCIENCES, 338 (1-2), p. 183-187|
|Abstract: ||Objective: To compare within-day variability of short (10 mwalking test at usual and fastest speed; 10MWT) and long (2 and 6-minute walking test; 2MWT/6MWT) tests in persons with multiple sclerosis.
Design: Observational study.
Setting: MS rehabilitation and research centers in Europe and US within RIMS (European network for best practice and research in MS rehabilitation).
Subjects: Ambulatory persons with MS (Expanded Disability Status Scale 0–6.5).
Intervention: Subjects of different centers performed walking tests at 3 time points during a single day.
Main measures: 10MWT, 2MWT and 6MWT at fastest speed and 10MWT at usual speed.
Ninety-five percent limits of agreement were computed using a random effects model with individual pwMS as random effect. Following this model, retest scores are with 95% certainty within these limits of baseline scores.
Results: In 102 subjects,within-day variability was constant in absolute units for the 10MWT, 2MWT and 6MWT at fastest speed (+/−0.26, 0.16 and 0.15 m/s respectively, corresponding to +/−19.2 m and +/−54 mfor the 2MWT and 6MWT) independent on the severity of ambulatory dysfunction. This implies a greater relative variability
with increasing disability level, often above 20% depending on the applied test. The relative within-day variability of the 10MWT at usual speed was +/−31% independent of ambulatory function.
Conclusions: Absolute values of within-day variability on walking tests at fastest speed were independent of disability level and greater with short compared to long walking tests. Relative within-day variability remained overall constant when measured at usual speed.|
|Notes: ||Feys, P (reprint author),Univ Hasselt, REVAL BIOMED Res Inst, Martelarenlaan 42, B-3500 Hasselt, Belgium.
|ISI #: ||000333883400032|
|Type: ||Journal Contribution|
|Validation: ||ecoom, 2015|
|Appears in Collections: ||Research publications|
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