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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/16799

Title: Within-day variability on short and long walking tests in persons with multiple sclerosis
Authors: FEYS, Peter
Bibby, Bo
Romberg, Anders
Santoyo, Carme
Gebara, Benoit
de Noordhout, Benoit Maertens
Knuts, Kathy
Bethoux, Francois
Skjerbaek, Anders
Jensen, Ellen
BAERT, Ilse
Vaney, Claude
de Groot, Vincent
Dalgas, Ulrik
Issue Date: 2014
Citation: JOURNAL OF THE NEUROLOGICAL SCIENCES, 338 (1-2), p. 183-187
Abstract: Objective: To compare within-day variability of short (10 mwalking test at usual and fastest speed; 10MWT) and long (2 and 6-minute walking test; 2MWT/6MWT) tests in persons with multiple sclerosis. Design: Observational study. Setting: MS rehabilitation and research centers in Europe and US within RIMS (European network for best practice and research in MS rehabilitation). Subjects: Ambulatory persons with MS (Expanded Disability Status Scale 0–6.5). Intervention: Subjects of different centers performed walking tests at 3 time points during a single day. Main measures: 10MWT, 2MWT and 6MWT at fastest speed and 10MWT at usual speed. Ninety-five percent limits of agreement were computed using a random effects model with individual pwMS as random effect. Following this model, retest scores are with 95% certainty within these limits of baseline scores. Results: In 102 subjects,within-day variability was constant in absolute units for the 10MWT, 2MWT and 6MWT at fastest speed (+/−0.26, 0.16 and 0.15 m/s respectively, corresponding to +/−19.2 m and +/−54 mfor the 2MWT and 6MWT) independent on the severity of ambulatory dysfunction. This implies a greater relative variability with increasing disability level, often above 20% depending on the applied test. The relative within-day variability of the 10MWT at usual speed was +/−31% independent of ambulatory function. Conclusions: Absolute values of within-day variability on walking tests at fastest speed were independent of disability level and greater with short compared to long walking tests. Relative within-day variability remained overall constant when measured at usual speed.
Notes: Feys, P (reprint author),Univ Hasselt, REVAL BIOMED Res Inst, Martelarenlaan 42, B-3500 Hasselt, Belgium. Peter.Feys@uhasselt.be
URI: http://hdl.handle.net/1942/16799
DOI: 10.1016/j.jns.2014.01.001
ISI #: 000333883400032
ISSN: 0022-510X
Category: A1
Type: Journal Contribution
Validation: ecoom, 2015
Appears in Collections: Research publications

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