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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/16799

Title: Within-day variability on short and long walking tests in persons with multiple sclerosis
Authors: FEYS, Peter
Bibby, Bo
Romberg, Anders
Santoyo, Carme
Gebara, Benoit
de Noordhout, Benoit Maertens
Knuts, Kathy
Bethoux, Francois
Skjerbaek, Anders
Jensen, Ellen
Vaney, Claude
de Groot, Vincent
Dalgas, Ulrik
Issue Date: 2014
Citation: JOURNAL OF THE NEUROLOGICAL SCIENCES, 338 (1-2), p. 183-187
Abstract: Objective: To compare within-day variability of short (10 mwalking test at usual and fastest speed; 10MWT) and long (2 and 6-minute walking test; 2MWT/6MWT) tests in persons with multiple sclerosis. Design: Observational study. Setting: MS rehabilitation and research centers in Europe and US within RIMS (European network for best practice and research in MS rehabilitation). Subjects: Ambulatory persons with MS (Expanded Disability Status Scale 0–6.5). Intervention: Subjects of different centers performed walking tests at 3 time points during a single day. Main measures: 10MWT, 2MWT and 6MWT at fastest speed and 10MWT at usual speed. Ninety-five percent limits of agreement were computed using a random effects model with individual pwMS as random effect. Following this model, retest scores are with 95% certainty within these limits of baseline scores. Results: In 102 subjects,within-day variability was constant in absolute units for the 10MWT, 2MWT and 6MWT at fastest speed (+/−0.26, 0.16 and 0.15 m/s respectively, corresponding to +/−19.2 m and +/−54 mfor the 2MWT and 6MWT) independent on the severity of ambulatory dysfunction. This implies a greater relative variability with increasing disability level, often above 20% depending on the applied test. The relative within-day variability of the 10MWT at usual speed was +/−31% independent of ambulatory function. Conclusions: Absolute values of within-day variability on walking tests at fastest speed were independent of disability level and greater with short compared to long walking tests. Relative within-day variability remained overall constant when measured at usual speed.
Notes: Feys, P (reprint author),Univ Hasselt, REVAL BIOMED Res Inst, Martelarenlaan 42, B-3500 Hasselt, Belgium. Peter.Feys@uhasselt.be
URI: http://hdl.handle.net/1942/16799
DOI: 10.1016/j.jns.2014.01.001
ISI #: 000333883400032
ISSN: 0022-510X
Category: A1
Type: Journal Contribution
Validation: ecoom, 2015
Appears in Collections: Research publications

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