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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/16579

Title: Endurance training is feasible in severely disabled patients with progressive multiple sclerosis.
Authors: Skjerbaek, A.
Naesby, M.
Lutzen, K.
Moller, A. Buch
Jensen, E.
Lamers, I.
Stenager, E.
Dalgas, U.
Issue Date: 2013
Citation: Multiple Sclerosis Journal, 20 (5), p. 627-630
Abstract: This study tested whether upper-body endurance training (ET) is feasible and can be performed at sufficient intensity to induce cardiovascular adaptations in severely disabled patients with progressive multiple sclerosis (MS). Eleven progressive MS patients (6.5 ≤ EDSS ≤ 8.0) scheduled for a four-week inpatient rehabilitation program were randomized to a control group (CON, n = 5) that received standard individualized MS rehabilitation or an intervention group (EXE, n = 6) that in addition received 10 sessions of predominantly upper-body ET. One patient dropped out of the EXE group (drop-out rate: 1/6~17%) and no adverse events were recorded. The EXE group completed on average 9.3±0.8 sessions (~96.0±5%). During the ET sessions an average heart rate of 93.9±9.3beats*min–1 were sustained corresponding to 91.6±6.8% of the maximal pre-intervention heart rate. In the EXE group a trend toward a time*group interaction was seen for VO2peak (p = 0.06). ET is feasible in severely disabled patients with progressive MS and it can probably be performed at sufficient intensity to induce cardiovascular adaptations.
URI: http://hdl.handle.net/1942/16579
DOI: 10.1177/1352458513505351
ISI #: 000333690400018
ISSN: 1352-4585
Category: A1
Type: Journal Contribution
Validation: ecoom, 2015
Appears in Collections: Research publications

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