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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15990

Title: Glycine receptors and brain development
Authors: AVILA MACAYA, Ariel
Nguyen, Laurent
RIGO, Jean-Michel
Issue Date: 2013
Abstract: Glycine receptors (GlyRs) are ligand-gated chloride ion channels that mediate fast inhibitory neurotransmission in the spinal cord and the brainstem. There, they are mainly involved in motor control and pain perception in the adult. However, these receptors are also expressed in upper regions of the central nervous system, where they participate in different processes including synaptic neurotransmission. Moreover, GlyRs are present since early stages of brain development and might influence this process. Here, we discuss the current state of the art regarding GlyRs during embryonic and postnatal brain development in light of recent findings about the cellular and molecular mechanisms that control brain development.
Notes: Rigo, JM (reprint author), Hasselt Univ, Martelarenlaan 42, B-4000 Hasselt, Belgium. jeanmichel.rigo@uhasselt.be
URI: http://hdl.handle.net/1942/15990
DOI: 10.3389/fncel.2013.00184
ISI #: 000326075200002
ISSN: 1662-5102
Category: A1
Type: Journal Contribution
Validation: ecoom, 2014
Appears in Collections: Research publications

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