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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15766

Title: Multifunctional Polymer Hybrid Nanoparticles for Biomedical Applications
Authors: Peters, Martijn
Advisors: ETHIRAJAN, Anitha
Issue Date: 2013
Publisher: tUL
Abstract: Multifunctional nanoparticles combine several properties into one stable construct, providing a very promising tool for the medical world. However, converting the theoretical designs into a usable application is a multi-step process that usually costs a lot of time, effort and money. Therefore, the aim of this thesis is to advance the research of designing multifunctional nanoparticles. The first part of the thesis covers the production of in situ surface functionalized polymer nanoparticles for targeting purposes. The second part of the thesis covers the production of fluorescent polymer nanoparticles, comprising of the conjugated polymer MDMO-PPV, for in vivo bioimaging. For the first time, these polymer nanoparticles were studied for their cytotoxicity and cell-uptake behavior using HMEC-1 cells. All the particles described in this work are synthesized using the miniemulsion technique.
Notes: master in de biomedische wetenschappen-bio-elektronica en nanotechnologie
URI: http://hdl.handle.net/1942/15766
Category: T2
Type: Theses and Dissertations
Appears in Collections: Master theses

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