Document Server@UHasselt >
Education >
School for Information Technology >
Master theses >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15711

Title: Estimation of vaccination coverage and waning immunity for measles, mumps, and rubella from serological surveys in Belgium, 2002 and 2006
Authors: De Carvalho Yokota, Renata Tiene
Advisors: HENS, Niel
Issue Date: 2013
Publisher: tUL
Abstract: In this report, two existing methods ignoring waning were fitted to the 2002 and 2006 serological surveys conducted in Belgium to estimate the vaccination coverage: the saturated model (Gay ,2000), and the restricted cubic splines (RCS) model for the exposure probabilities (Goeyvaerts et al., 2012). In addition, an extension of these models to include waning of immunity to estimate the vaccination coverage, as recently developed by Wood, Goeyvaerts, and Hens (unpublished manuscript), was fitted. Among the methods ignoring waning, the best models were the RCS model with five and three knots for the 2002 and 2006 data, respectively. By including waning parameters, the vaccination coverage for older birth cohorts was largerWhen relying on the waning model, mumps presented the lowest seroconversion rate (0.92).The estimated waning parameters were '0.0050, 0.0045 , and 0 for measles, mumps, and rubella, respectively. The vaccination coverage was lower than the target of 90% of the WHO.
Notes: Master of Statistics-Biostatistics
URI: http://hdl.handle.net/1942/15711
Category: T2
Type: Theses and Dissertations
Appears in Collections: Master theses

Files in This Item:

Description SizeFormat
N/A7.88 MBAdobe PDF

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.