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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/1571

Title: A comparison of procedures to correct for base-line differences in the analysis of continuous longitudinal data: a case-study
Authors: VERBEKE, Geert
Fieuws, S
LESAFFRE, Emmanuel
Kato, B.S.
Foreman, M.D.
Broos, P.L.O.
Milisen, Koen
Issue Date: 2006
Citation: JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 55(1). p. 93-101
Abstract: The main advantage of longitudinal studies is that they can distinguish changes over time within individuals (longitudinal effects) from differences between subjects at the start of the study (base-line characteristics; cross-sectional effects). Often, especially in observational studies, subjects are very heterogeneous at base-line, and one may want to correct for this, when doing inferences for the longitudinal trends. Three procedures for base-line correction are compared in the context of linear mixed models for continuous longitudinal data. All procedures are illustrated extensively by using data from an experiment which aimed at studying the relationship between the post-operative evolution of the functional status of elderly hip fracture patients and their preoperative neurocognitive status.
URI: http://hdl.handle.net/1942/1571
DOI: 10.1111/j.1467-9876.2005.00531.x
ISI #: 000235710800007
ISSN: 0035-9254
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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