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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15521

Title: Contribution of respiratory pathogens to influenza-like illness consultations
Authors: BOLLAERTS, Kaatje
Antoine, J.
Van Casteren, V.
Ducoffre, G.
HENS, Niel
Quoilin, S.
Issue Date: 2013
Citation: EPIDEMIOLOGY AND INFECTION, 141 (10), p. 2196-2204
Abstract: Influenza-like illnesses (ILIs) are caused by several respiratory pathogens. These pathogens show weak to strong seasonal activity implying seasonality in ILI consultations. In this paper, the contribution of pathogens to seasonality of ILI consultations was statistically modelled. Virological count data were first smoothed using modulation models for seasonal time series. Second, Poisson regression was used regressing ILI consultation counts on the smoothed time series. Using ratios of the estimated regression parameters, relative measures of the under-reporting of pathogens were obtained. Influenza viruses A and B, parainfluenza virus and respiratory syncytial virus (RSV) significantly contributed to explain the seasonal variation in ILI consultations. We also found that RSV was the least and influenza virus A is the most underreported pathogen in Belgian laboratory surveillance. The proposed methods and results are helpful in interpreting the data of clinical and laboratory surveillance, which are the essential parts of influenza surveillance.
Notes: [Bollaerts, K.; Antoine, J.; Van Casteren, V.; Ducoffre, G.; Quoilin, S.] Sci Inst Publ Hlth, Operat Directorate Publ Hlth & Surveillance, B-1050 Brussels, Belgium. [Hens, N.] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Diepenbeek, Belgium. [Hens, N.] Univ Antwerp, Vaccine & Infect Dis Inst, Ctr Evaluat Vacciniat, Ctr Hlth Econ Res & Modelling Infect Dis, Antwerp, Belgium. kaatje.bollaerts@wiv-isp.be
URI: http://hdl.handle.net/1942/15521
DOI: 10.1017/S0950268812002506
ISI #: 000323887200024
ISSN: 0950-2688
Category: A1
Type: Journal Contribution
Validation: ecoom, 2014
Appears in Collections: Research publications

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