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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15423

Title: Reduced graphene oxide micropatterns as an interface for adherent cells
Authors: Delle, Lotta E.
Lanche, Ruben
Law, Jessica Ka-Yan
Weil, Maryam
Xuan Thang, Vu
Wagner, Patrick
Ingebrandt, Sven
Issue Date: 2013
Publisher: WILEY-V C H VERLAG GMBH
Citation: PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, 210 (5), p. 975-982
Abstract: In the present study, reduced graphene oxide (rGO) is used as a biointerface for the investigation of cell adhesion of human embryonic kidney (HEK 293) cells. A fast, straightforward, and substrate-independent soft lithography approach known as Micromolding In Capillaries (MIMIC) was utilized to pattern graphene oxide (GO) arrays. Large-scale GO patterns with widths and distances in the micrometer range were obtained and were subsequently reduced to rGO via an environmentally-friendly procedure using L-ascorbic acid. Physical characterization of rGO patterns and cells was performed by optical microscopy, atomic force microscopy, and scanning electron microscopy. Impedance spectroscopy was used for the electrochemical characterization of GO before and after reduction. Cell adhesion and alignment was strong on the rGO micropatterns. In future assays, the rGO could combine two functions: cellular patterning and electrical interfacing of cells. HEK 293 cells aligning on rGO micro patterns (SEM image)
Notes: Univ Appl Sci Kaiserslautern, Dept Informat & Microsyst Technol, D-66482 Zweibrucken, Germany. Hasselt Univ, Inst Mat Res, B-3590 Diepenbeek, Belgium.
URI: http://hdl.handle.net/1942/15423
DOI: 10.1002/pssa.201200864
ISI #: 000319151900024
ISSN: 1862-6300
Category: A1
Type: Journal Contribution
Validation: ecoom, 2014
Appears in Collections: Research publications

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