Document Server@UHasselt >
Research publications >
Please use this identifier to cite or link to this item:
|Title: ||Non-invasive cardiovascular profiling using combined electrocardiogram-Doppler ultrasonography and impedance cardiography: An experimental approach|
|Authors: ||TOMSIN, Kathleen|
|Issue Date: ||2013|
|Citation: ||CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 40 (7), p. 438-442|
|Abstract: ||In the present study, the feasibility of cardiovascular profiling using both combined electrocardiogram (ECG)-Doppler ultrasonography and impedance cardiography (ICG) was evaluated. Fourteen non-pregnant healthy women received 500mL saline solution (NaCl 0.9% at 999mL/h) intravenously by steady state infusion. Before and after this acute volume loading, we measured orthostatic-challenged cardiac and arterial characteristics using ICG and assessed venous characteristics by combined ECG-Doppler before and during the Valsalva manoeuvre. Changes are expressed as the mean +/- SEM and were evaluated by the one-sample Wilcoxon signed-rank test. After volume loading, the observed fall in stroke volume after postural change from supine to standing decreased (-14 +/- 3 vs -23 +/- 2%; P=0.011). Hepatic A wave velocity increased 63 +/- 28% after volume loading (P=0.007) and decreased during the Valsalva manoeuvre (-205 +/- 21%; P=0.001). Volume loading raised the thoracic fluid content index in both the supine and standing positions (7 +/- 2% and 10 +/- 1%, respectively; P0.014). Combined ECG-Doppler ultrasonography and ICG enables the non-invasive identification of concomitant haemodynamic changes at the level of the heart, the arterial bed and the venous compartment. Our data support the view that non-invasive cardiovascular profiling is feasible, which seems particularly useful for the evaluation of patients who are not critically ill, such as pregnant women.|
|Notes: ||Tomsin, K (reprint author), Ziekenhuis Oost Limburg, Dept Obstet & Gynaecol, B-3600 Genk, Belgium. Hasselt Univ, Fac Med & Life Sci, Diepenbeek, Belgium.
|ISI #: ||000320781400007|
|Type: ||Journal Contribution|
|Validation: ||ecoom, 2014|
|Appears in Collections: ||Research publications|
Files in This Item:
|published version||219.96 kB||Adobe PDF|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.