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|Title: ||Voluntary feed intake and leptin sensitivity in ad libitum fed obese ponies following a period of restricted feeding: a pilot study|
|Authors: ||Van Weyenberg, S.|
Kalmar, I. D.
Janssens, G. P. J.
|Issue Date: ||2013|
|Citation: ||JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 97 (4), p. 624-631|
|Abstract: ||The relation between plasma leptin and daily ad libitum roughage intake was evaluated during a 14-day period in eight obese Shetland ponies. When the feeding strategy was changed from maintenance feeding to ad libitum feeding, feed intake increased the first day, decreased the second day and increased again during the following days to reach a constant level after 8days. Plasma leptin concentration increased during the first 2days, but remained constant afterwards. Although the same pattern was found in all ponies, the magnitude of the increase in leptin on day 1 and the resulting decrease in feed intake on day 2 differed between ponies. A lower anorectic effect was seen in ponies with higher initial leptin concentration, suggesting the presence of different degrees in leptin sensitivity in obese ponies. High leptin production in a attempt to compensate for the decrease in leptin sensitivity might explain large variations in plasma leptin among obese ponies with similar body condition score. Further research is necessary to clarify whether the reduced leptin sensitivity precedes obesity in equines or vice versa.|
|Notes: ||[Van Weyenberg, S.] Inst Agr & Fisheries Res, Technol & Food Sci Unit, Merelbeke, Belgium. [Van Weyenberg, S.; Kalmar, I. D.; Janssens, G. P. J.] Univ Ghent, Anim Nutr Lab, Merelbeke, Belgium. [Buyse, J.; Swennen, Q.] Catholic Univ Louvain, Lab Physiol Immunol & Genet Domest Anim, B-3000 Louvain, Belgium. [Swennen, Q.] Hasselt Univ, Ctr Environm Sci, Diepenbeek, Belgium.
|ISI #: ||000321567100003|
|Type: ||Journal Contribution|
|Validation: ||ecoom, 2014|
|Appears in Collections: ||Research publications|
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