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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15360

Title: Long-term TENS treatment decreases cortical motor representation in multiple sclerosis
Authors: CUYPERS, Koen
LEENUS, Daphnie
van den Berg, Femke
Levin, Oron
THIJS, Herbert
Swinnen, Stephan
Issue Date: 2013
Citation: NEUROSCIENCE, 250, p. 1-7
Abstract: This study investigated the effect of a long-term transcutaneous electrical nerve stimulation (TENS) treatment on cortical motor representation in patients with multiple sclerosis (MS). In this double blind crossover design, patients received either TENS or sham stimulation for 3 weeks (1 hour per day) on the median nerve region of the most impaired hand, followed by the other stimulation condition after a washout period of 6 months. Cortical motor representation was mapped using transcranial magnetic stimulation (TMS) at baseline and after the 3-week stimulation protocol. Our results revealed that three weeks of daily stimulation with TENS significantly decreased the cortical motor representation of the stimulated muscle in MS patients. Although the mechanisms underlying this decrease remain unclear, our findings indicate that TENS has the ability to induce long-term reorganization in the motor cortex of MS patients.
Notes: Meesen, RLJ (reprint author), REVAL Res Inst, Agoralaan,Bldg A, B-3590 Diepenbeek, Belgium. raf.meesen@uhasselt.be
URI: http://hdl.handle.net/1942/15360
DOI: 10.1016/j.neuroscience.2013.06.046
ISI #: 000324847400001
ISSN: 0306-4522
Category: A1
Type: Journal Contribution
Validation: ecoom, 2014
Appears in Collections: Research publications

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