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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15190

Title: The role of the kinase OXI1 in cadmium- and copper-induced molecular responses in Arabidopsis thaliana
Authors: Smeets, Karen
Opdenakker, Kelly
Remans, Tony
Forzani, Celine
Hirt, Heribert
Vangronsveld, Jaco
Cuypers, Ann
Issue Date: 2013
Citation: PLANT CELL AND ENVIRONMENT, 36 (6), p. 1228-1238
Abstract: The hypothesis that mitogen-activated protein kinase (MAPK) signalling is important in plant defences against metal stress has become accepted in recent years. To test the role of oxidative signal-inducible kinase (OXI1) in metal-induced oxidative signalling, the responses of oxi1 knockout lines to environmentally realistic cadmium (Cd) and copper (Cu) concentrations were compared with those of wild-type plants. A relationship between OXI1 and the activation of lipoxygenases and other initiators of oxylipin production was observed under these stress conditions, suggesting that lipoxygenase-1 may be a downstream component of OXI1 signalling. Metal-specific differences in OXI1 action were observed. For example, OXI1 was required for the up-regulation of antioxidative defences such as catalase in leaves and Fe-superoxide dismutase in roots, following exposure to Cu, processes that may involve the MEKK1-MKK2-WRKY25 cascade. Moreover, the induction of Cu/Zn superoxide dismutases in Cu-exposed leaves was regulated by OXI1 in a manner that involves fluctuations in the expression of miRNA398. These observations contrast markedly with the responses to Cd exposure, which also involves OXI1-independent pathways but rather involves changes in components mediating intracellular communication.
Notes: Hasselt Univ, Ctr Environm Sci, B-3590 Diepenbeek, Belgium. URGV Plant Genom, F-91057 Evry, France.
URI: http://hdl.handle.net/1942/15190
DOI: 10.1111/pce.12056
ISI #: 000318176800013
ISSN: 0140-7791
Category: A1
Type: Journal Contribution
Validation: ecoom, 2014
Appears in Collections: Research publications

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