Document Server@UHasselt >
Research publications >
Please use this identifier to cite or link to this item:
|Title: ||Non-Hodgkin Lymphoma after treatment with Extended dosing temozolomide and radiotherapy for a glioblastoma: A case report|
|Authors: ||Van Ginderachter, Laura|
|Issue Date: ||2013|
|Citation: ||Case Report Oncology, 6, p. 45-49|
|Abstract: ||Temozolomide (TMZ) is an alkylating agent, used for the treatment of high-grade gliomas. This case report describes the development of a non-Hodgkin lymphoma in a patient treated with extended-dose temozolomide and radiotherapy. In addition to the possible mutagenic effect of temozolomide – as described for all alkylating agents – there might have been an immunosuppressive effect of TMZ. The pathological appearance of the lymphoma as well as the presence of a grade 3 lymphopenia early in treatment supports this hypothesis. As the use of TMZ increases, the awareness that TMZ may induce secondary malignancies should increase as well.|
|Type: ||Journal Contribution|
|Appears in Collections: ||Research publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.