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|Title: ||High susceptibility to cytomegalovirus infection of pregnant women in Flanders, Belgium|
|Authors: ||Leuridan, E.|
Van Damme, P.
|Issue Date: ||2012|
|Citation: ||Facts, views & vision in ObGyn, 4 (2), p. 76-81|
|Abstract: ||Maternal antibodies against cytomegalovirus(CMV) infection offer, to some extent, protection against congenital
Thisstudy describesthe seroprevalence of CMV-specific IgGin 220 parturient women during pregnancy, at delivery,
at 3 months after delivery and in their cord blood (Flanders,Belgium, 2006-2008).ELISA was used to measure IgG.
Ofthis population, 30% had positive IgG titres. Active transplacentaltransport was confirmed with a ratio 1.15/1.
Elevated maternalIgGtitre and increased parity, but not age, were significantly associated with higherseroprevalence of CMV-specific IgG in the cord blood.
These data indicate a high susceptibility to CMV among fertile women.Prenatal prevention and otherstrategiesto
prevent intra-uterine infection are of critical importance in a highly susceptible population.|
|Type: ||Journal Contribution|
|Appears in Collections: ||Research publications|
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