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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/14737

Title: High susceptibility to cytomegalovirus infection of pregnant women in Flanders, Belgium
Authors: Leuridan, E.
Ieven, M.
Hens, N.
Van Damme, P.
Issue Date: 2012
Citation: Facts, views & vision in ObGyn, 4 (2), p. 76-81
Abstract: Maternal antibodies against cytomegalovirus(CMV) infection offer, to some extent, protection against congenital CMV infection. Thisstudy describesthe seroprevalence of CMV-specific IgGin 220 parturient women during pregnancy, at delivery, at 3 months after delivery and in their cord blood (Flanders,Belgium, 2006-2008).ELISA was used to measure IgG. Ofthis population, 30% had positive IgG titres. Active transplacentaltransport was confirmed with a ratio 1.15/1. Elevated maternalIgGtitre and increased parity, but not age, were significantly associated with higherseroprevalence of CMV-specific IgG in the cord blood. These data indicate a high susceptibility to CMV among fertile women.Prenatal prevention and otherstrategiesto prevent intra-uterine infection are of critical importance in a highly susceptible population.
URI: http://hdl.handle.net/1942/14737
ISSN: 2032-0418
Category: A1
Type: Journal Contribution
Appears in Collections: Research publications

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