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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/14310

Title: The Prevention and Treatment of Missing Data in Clinical Trials
Authors: Little, Roderick J.
D'Agostino, Ralph
Cohen, Michael L.
Dickersin, Kay
Emerson, Scott S.
Farrar, John T.
Frangakis, Constantine
Hogan, Joseph W.
Molenberghs, Geert
Murphy, Susan A.
Neaton, James D.
Rotnitzky, Andrea
Scharfstein, Daniel
Shih, Weichung J.
Siegel, Jay P.
Stern, Hal
Issue Date: 2012
Publisher: MASSACHUSETTS MEDICAL SOC
Citation: NEW ENGLAND JOURNAL OF MEDICINE, 367 (14), p. 1355-1360
Abstract: Missing data in clinical trials can have a major effect on the validity of the inferences that can be drawn from the trial. This article reviews methods for preventing missing data and, failing that, dealing with data that are missing.
Notes: [Little, Roderick J.] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA. [Murphy, Susan A.] Univ Michigan, Dept Stat, Ann Arbor, MI 48109 USA. [D'Agostino, Ralph] Boston Univ, Dept Math & Stat, Boston, MA 02215 USA. [Cohen, Michael L.] Natl Res Council Natl Acad, Washington, DC USA. [Dickersin, Kay] Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD USA. [Frangakis, Constantine; Scharfstein, Daniel] Johns Hopkins Univ, Dept Biostat, Baltimore, MD 21205 USA. [Emerson, Scott S.] Univ Washington, Dept Biostat, Seattle, WA 98195 USA. [Farrar, John T.] Univ Penn, Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA. [Hogan, Joseph W.] Brown Univ, Ctr Stat Sci, Program Publ Hlth, Providence, RI 02912 USA. [Molenberghs, Geert] Univ Hasselt, Int Inst Biostat & Stat Bioinformat, Louvain, Belgium. [Molenberghs, Geert] Katholieke Univ Leuven, Louvain, Belgium. [Neaton, James D.] Univ Minnesota, Sch Publ Hlth, Minneapolis, MN USA. [Rotnitzky, Andrea] Univ Torcuato Di Tella, Dept Econ, Buenos Aires, DF, Argentina. [Shih, Weichung J.] Univ Med & Dent New Jersey, Sch Publ Hlth, Dept Biostat, New Brunswick, NJ USA. [Siegel, Jay P.] Johnson & Johnson Consumer Prod Inc, Radnor, PA USA. [Stern, Hal] Univ Calif Irvine, Dept Stat, Irvine, CA USA.
URI: http://hdl.handle.net/1942/14310
DOI: 10.1056/NEJMsr1203730
ISI #: 000309406100016
ISSN: 0028-4793
Category: A1
Type: Journal Contribution
Validation: ecoom, 2013
Appears in Collections: Research publications

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