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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/12862

Title: Study protocol of KLIMOP: a cohort study on the wellbeing of older cancer patients in Belgium and the Netherlands
Authors: Deckx, Laura
van Abbema, Doris
Nelissen, Katherine
Daniels, Liesbeth
Stinissen, Piet
Bulens, Paul
Linsen, Loes
Rummens, Jean-Luc
Robaeys, Geert
de Jonge, Eric T.
Houben, Bert
Pat, Karin
Walgraeve, Daan
Spaas, Luc
Verheezen, Jolanda
Verniest, Thessa
Goegebuer, Alexander
Wildiers, Hans
van den Berkmortel, Franchette
Tjan-Heijnen, Vivianne C.
Buntinx, Frank
van den Akker, Marjan
Issue Date: 2011
Abstract: Background: Cancer is mainly a disease of older patients. In older cancer patients, additional endpoints such as quality of survival and daily functioning might be considered equally relevant as overall or disease free survival. However, these factors have been understudied using prospective designs focussing on older cancer patients. Therefore, this study will focus on the impact of cancer, ageing, and their interaction on the long-term wellbeing of older cancer patients. Methods/Design: This study is an observational cohort study. We aim to recruit 720 cancer patients above 70 years with a new diagnosis of breast, prostate, lung or gastrointestinal cancer and two control groups: one control group of 720 patients above 70 years without a previous diagnosis of cancer and one control group of 720 cancer patients between 50 - 69 years newly diagnosed with breast, prostate, lung or gastrointestinal cancer. Data collection will take place at inclusion, after six months, after one year and every subsequent year until death or end of the study. Data will be collected through personal interviews (consisting of socio-demographic information, general health information, a comprehensive geriatric assessment, quality of life, health locus of control and a loneliness scale), a handgrip test, assessment of medical records, two buccal swabs and a blood sample from cancer patients (at baseline). As an annex study, caregivers of the participants will be recruited as well. Data collection for caregivers will consist of a self-administered questionnaire examining depression, coping, and burden. Discussion: This extensive data collection will increase insight on how wellbeing of older cancer patients is affected by cancer (diagnosis and treatment), ageing, and their interaction. Results may provide new insights, which might contribute to the improvement of care for older cancer patients.
Notes: [Deckx, L; Daniels, L; Buntinx, F; van den Akker, M] Katholieke Univ Leuven, Dept Gen Practice, B-3000 Louvain, Belgium. [van Abbema, D; Tjan-Heijnen, VC] Maastricht Univ Med Ctr, Dept Med Oncol, GROW Sch Oncol & Dev Biol, NL-6202 AZ Maastricht, Netherlands. [Nelissen, K; Stinissen, P; Rummens, JL; Robaeys, G] Hasselt Univ, Fac Med, B-3590 Diepenbeek, Belgium. [Bulens, P] Limburgs Oncol Ctr, B-3500 Hasselt, Belgium. [Linsen, L; Rummens, JL] Jessa Hosp, Biobank & Clin Lab Expt Hematol, B-3500 Hasselt, Belgium. [Robaeys, G] Ziekenhuis Oost Limburg, Dept Gastroenterol, B-3600 Genk, Belgium. [de Jonge, ET] Ziekenhuis Oost Limburg, Dept Gynaecol, B-3600 Genk, Belgium. [Houben, B; Walgraeve, D] Jessa Hosp, Dept Gastroenterol, B-3500 Hasselt, Belgium. [Pat, K; Spaas, L] Jessa Hosp, Dept Pulmonol, B-3500 Hasselt, Belgium. [Verheezen, J] Reg Ziekenhuis Sint Trudo, Dept Med Oncol, B-3800 St Truiden, Belgium. [Verniest, T] Reg Ziekenhuis Heilig Hart Leuven, Dept Pulmonol, B-3000 Louvain, Belgium. [Goegebuer, A] Reg Ziekenhuis Heilig Hart Leuven, Dept Gastroenterol, B-3000 Louvain, Belgium. [Wildiers, H] Univ Hosp Leuven, Dept Gen Med Oncol, B-3000 Louvain, Belgium. [van den Berkmortel, F] Atrium Med Ctr Parkstad, Dept Internal Med, NL-6401 CX Heerlen, Netherlands. [Buntinx, F; van den Akker, M] Maastricht Univ, Dept Gen Practice, CAPHRI Sch Publ Hlth & Primary Care, NL-6200 MD Maastricht, Netherlands.
URI: http://hdl.handle.net/1942/12862
DOI: 10.1186/1471-2458-11-825
ISI #: 000296973900001
ISSN: 1471-2458
Category: A1
Type: Journal Contribution
Validation: ecoom, 2012
Appears in Collections: Research publications

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