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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/12558

Title: Optimalisatie en miniaturisatie van een NCD-gebaseerde immunosensor
Authors: Bex, Jan
Advisors: WAGNER, Patrick
Issue Date: 2010
Publisher: tUL Diepenbeek
Abstract: C-reactief protein (CRP) is a significant marker for inflammatory diseases. Recent research also indicates that high CRP-concentrations in blood are a definite risk marker for cardiovascular diseases. Current standards for CRP-detection include turbidimetric and ELISA-assays. These methods are time-consuming, expensive and require educated medical personnel. An electronic antigen detection system could allow for a faster, simple and real-time determination. In this study an existing immunosensing platform will be optimalized and miniaturized. The immunosensor is based on nanocrystalline diamond (NCD), a very appealing material for biosensing purposes because of its interesting properties, namely biocompatibility, chemical inertia and the ability to change the electrical behavior through doping. A recent study proves that a NCD-based immunosensor could detect CRP with electrochemical impedance spectroscopy (EIS). This sensor will be miniaturized to a coplanar setup for future use in a
Notes: master in de biomedische wetenschappen-bio-elektronica en nanotechnologie
URI: http://hdl.handle.net/1942/12558
Category: T2
Type: Theses and Dissertations
Appears in Collections: Master theses

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