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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/12304

Title: Invasive fungal infection in an elderly patient with defective inflammatory macrophage function
Authors: Chai, L. Y. A.
Naesens, R.
Khoo, A. L.
Abeele, M. V.
van Renterghem, K.
Cartuyvels, R.
Netea, M. G.
GYSSENS, Inge
Issue Date: 2011
Publisher: WILEY-BLACKWELL
Citation: CLINICAL MICROBIOLOGY AND INFECTION, 17 (10). p. 1546-1549
Abstract: Macrophages are known to be involved in pathogen recognition and mediate host immune responses, but, in the clinical setting, their purported central role in opportunistic fungal infections has not been demonstrated to date. Herein, we describe a patient with invasive testicular aspergillosis in whom we found, for the first time, a defect in macrophage function.
Notes: [Gyssens, IC] Jessa Hosp, Dept Infect Dis, B-3500 Hasselt, Belgium. [Gyssens, IC] Hasselt Univ, Diepenbeek, Belgium. [Gyssens, IC] Canisius Wilhelmina Hosp, Dept Med Microbiol, Nijmegen, Netherlands. [Chai, LYA; Khoo, AL; Netea, MG; Gyssens, IC] Radboud Univ Nijmegen, Dept Med, Med Ctr, NL-6525 ED Nijmegen, Netherlands. [Chai, LYA; Khoo, AL; Netea, MG; Gyssens, IC] Nijmegen Inst Infect Inflammat & Immun N4i, Nijmegen, Netherlands. [Chai, LYA] Natl Univ Hlth Syst, Univ Med Cluster, Div Infect Dis, Singapore, Singapore. [Naesens, R; Cartuyvels, R] Jessa Hosp, Lab Med Microbiol, B-3500 Hasselt, Belgium. [Abeele, MV] Jessa Hosp, Dept Geriatr Med, B-3500 Hasselt, Belgium. [van Renterghem, K] Jessa Hosp, Dept Urol, B-3500 Hasselt, Belgium. i.gyssens@aig.umcn.nl
URI: http://hdl.handle.net/1942/12304
DOI: 10.1111/j.1469-0691.2011.03598.x
ISI #: 000295086100018
ISSN: 1198-743X
Category: A1
Type: Journal Contribution
Validation: ecoom, 2012
Appears in Collections: Research publications

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