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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/12129

Title: Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H(2)O(2))
Authors: Reisert, Steffen
Geissler, Hanno
Floerke, Rudolf
Naether, Niko
WAGNER, Patrick
Schoening, Michael J.
Issue Date: 2011
Abstract: The presented work focuses on the development of a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour. In a first step, selected commercially available gas sensors have been investigated on cross-sensitivity towards hydrogen peroxide vapour and humidity. An MOX (TGS 816, Figaro) and a solid-electrolyte gas sensor (SO-A0-250, Electrovac) (lambda-probe) have shown good characteristics in terms of sensitivity towards HPV, considering also reproducibility, long-term drift and stability. Further, the sterilization effect of HPV has been investigated by means of the microbial reduction test. A correlation between the microbial reduction of Bacillus subtilis spores and the sensor response in hydrogen peroxide atmosphere has been established. Based on this correlation the microbial reduction may be estimated by means of the sensor output over a wide range of parameters. (C) 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Notes: [Reisert, S; Nather, N; Schoning, MJ] Aachen Univ Appl Sci, Inst Nano & Biotechnol, D-52428 Julich, Germany [Geissler, H; Florke, R] SIG Combibloc Syst GmbH, D-52441 Linnich, Germany [Wagner, P] Hasselt Univ, Inst Mat Res, B-3590 Diepenbeek, Belgium schoening@fh-aachen.de
URI: http://hdl.handle.net/1942/12129
DOI: 10.1002/pssa.201001138
ISI #: 000292945800024
ISSN: 1862-6300
Category: A1
Type: Journal Contribution
Validation: ecoom, 2012
Appears in Collections: Research publications

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