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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/11867

Title: The cellular redox state as a modulator in cadmium and copper responses in Arabidopsis thaliana seedlings
Authors: Cuypers, Ann
Smeets, Karen
Ruytinx, Joske
Opdenakker, Kelly
Keunen, Els
Remans, Tony
Horemans, Nele
Vanhoudt, Nathalie
Van Sanden, Suzy
Van Belleghem, Frank
Guisez, Yves
Colpaert, Jan V.
Vangronsveld, Jaco
Issue Date: 2011
Citation: JOURNAL OF PLANT PHYSIOLOGY, 168(4). p. 309-316
Abstract: The cellular redox state is an important determinant of metal phytotoxicity. In this study we investigated the influence of cadmium (Cd) and copper (Cu) stress on the cellular redox balance in relation to oxidative signalling and damage in Arabidopsis thaliana. Both metals were easily taken up by the roots, but the translocation to the aboveground parts was restricted to Cd stress. In the roots, Cu directly induced an oxidative burst, whereas enzymatic ROS (reactive oxygen species) production via NADPH oxidases seems important in oxidative stress caused by Cd. Furthermore, in the roots, the glutathione metabolism plays a crucial role in controlling the gene regulation of the antioxidative defence mechanism under Cd stress. Metal-specific alterations were also noticed with regard to the microRNA regulation of CuZnSOD gene expression in both roots and leaves. The appearance of lipid peroxidation is dual: it can be an indication of oxidative damage as well as an indication of oxidative signalling as lipoxygenases are induced after metal exposure and are initial enzymes in oxylipin biosynthesis. In conclusion, the metal-induced cellular redox imbalance is strongly dependent on the chemical properties of the metal and the plant organ considered. The stress intensity determines its involvement in downstream responses in relation to oxidative damage or signalling. (C) 2010 Elsevier GmbH. All rights reserved.
Notes: [Ann, Cuypers] Hasselt Univ, Ctr Environm Sci, B-3590 Diepenbeek, Belgium. [Nele, Horemans; Nathalie, Vanhoudt] Belgian Nucl Res Ctr SCK CEN, B-2400 Mol, Belgium. [Frank, Van Belleghem] Open Univ Netherlands, Sch Sci, NL-6401 DL Heerlen, Netherlands. [Yves, Guisez] Univ Antwerp, Dept Biol, B-2020 Antwerp, Belgium.
URI: http://hdl.handle.net/1942/11867
DOI: 10.1016/j.jplph.2010.07.010
ISI #: 000288721100002
ISSN: 0176-1617
Category: A1
Type: Journal Contribution
Validation: ecoom, 2012
Appears in Collections: Research publications

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